Models of inheritance Flashcards
1
Q
What is the definition of dominant autosomal?
A
A characteristic is dominant if it manifests in a heterozygote
2
Q
What is a gain of function autosomal disorder?
A
The affected gene now makes proteins with a new function
3
Q
What is a dominant negative effect?
A
The mutated form interferes with the activity of the protein it binds
4
Q
What is an insufficient autosomal disorder?
A
A mutant in one gene results in 1/2 the amount of protein, which is not enough for normal function
