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Step 1 > Mnemonics > Flashcards

Mnemonics Flashcards

1
Q

Therapeutic Index: TILE

A

Therapeutic Index =

Lethal dose 50 / Effective dose 50

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2
Q

P450 Inducers: Kenytoin

A

Kenytoin Must Ride Shotgun in Barbies Girl CCar

Phenytoin
Modafinil
Rifampin
St. John's Wart
Barbiturates
Griseofulvin
Carbamazepine
Chronic alcohol use
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3
Q

Zero Order Drugs: PEA

A

Phenytoin, Ethanol, Aspirin (at high/toxic conc.)

Zero order is linear

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4
Q

P450 Inhibitors: MAGIC RACKS in GQ

A 
Macrolides
Amiodarone
Grapefruit juice
Isoniazid
Cimetidine
Ritonavir
Acute alcohol abuse
Ciprofloxacin
Ketoconazole
Sulfonamides

Gemfibrozil
Quinidine

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5
Q

Phase II Drug Metabolism

geriatric patients have GAS

A

Phase II undergo conjugation –> GAS
Glucuronidation
Acetylation
Sulfation

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Step 1 (12 decks)

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