MITOSIS Flashcards

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1
Q

What are the 2 methods of cell division

A

mitosis

meiosis

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2
Q

What is the basic outline of mitosis

A

2 daugher cells produced that each have the same number of chromosomes as the parent cell

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3
Q

What is the basic outline of meiosis

A

4 daughter cells produced that eahc have half the number of chromosomes as the parent cell

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4
Q

What are the 5 stages of mitosis in order

A

1) prophase
2) metaphase
3) anaphase
4) telophase

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5
Q

What is mitosis needed for

A

the growth of multicellular organisms and for repairing damaged tissues

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6
Q

What is in the cell cycle

A

interphase (Gap phase 1, synthesis, Gap phase 2) -> mitosis

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7
Q

What happens during Gap phase 1

A

cell grows and new organelles & proteins are made

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8
Q

What happens during synthesis

A

cell replicates its DNA so that its ready to divide by mitosis

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9
Q

When is the genes of the 2 daughter cells different to the parent cells

A

when a mutation occurs

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10
Q

What 3 things occur during interphase

A

1) DNA is unravelled and replicated
2) organelles are replicated
3) ATP content is doubled

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11
Q

Why is the ATP content doubled during interphase

A

ATP provides the energy needed for cell division

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12
Q

What occurs during prophase (4 points)

A

1) chromosomes become visible as long thin threads and change to shorter and fatter
2) centrioles (only found in animals) move to opposite ends
3) spindle fibres develop from each centriole to form spindle apparatus
4) nuclear envelope breaks down so chromosomes are left free in the cutoplasm, drawn towards the equator of the cell

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13
Q

What occurs during metaphase (2 points)

A

1) chromosomes line up along the middle of the cell

2) spindle fibres attach to the centromere

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14
Q

What is the centromere

A

where chromatids are joined

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15
Q

What are chromatids

A

what chromosomes are made up of

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16
Q

How many strands of chromatids in a chromosome

A

2

17
Q

What occurs during anaphase (2 points)

A

1) centromeres divide into 2
2) spindle fibres contract, so pull the individual chromatids in the chromosome apart and towards the opposite poles of the spindle

18
Q

What shape do the chromatids appear during anaphase

A

v-shaped

19
Q

Where is the energy for anaphase provided from and where do they gather

A

mitochondria , gather around the spindle fibres

20
Q

What occurs during telophase

A

1) chromatids reach the opposite poles on the spindle
2) chromatids become longer and thinner before disappearing
3) spindle fibres disintegrate
4) nuclear envelope and nucleolus re-form
5) cytokinesis

21
Q

What is cytokinesis

A

cytoplasm divides to form 2 daughter cells that are genetically identical

22
Q

What are the 3 functions of mitosis

A

1) growth
2) repair
3) reproduction

23
Q

What is cancer the result of

A

uncontrolled cell division due to a gene mutation

24
Q

What is mitosis and cell division controlled by

A

genes

25
Q

What are some treatments of cancer designed to control and how

A

the rate of cell division by disrupting the cell cycle

26
Q

What are the 2 main stages that cancer treatments target

A

G1 and S phase

27
Q

What drugs target G1 phase

A

chemical drugs

28
Q

What drugs target the S phase

A

radiation and some drugs

29
Q

How do chemical drugs target the G1 phase

A

prevent the synthesis of enzmes

30
Q

How does radiation & some drugs target the S phase

A

damages DNA which is detected, and the cell will kill itself

31
Q

What is the problem with targeting cell division to cure cancer

A

the drugs cannot distinguish between normal body & cancer cells