B LYMPHOCYTES AND HUMORAL IMMUNITY Flashcards

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1
Q

How does the antigen enter the B cell

A

endocytosis

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2
Q

What happens after endocytosis

A

it gets presented on the surfaced (processed), and T-cells bind to the processes antigens & stimulates the B-cell to divide by mitsos

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3
Q

What does the division of B-cells produce

A

plasma cells

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4
Q

What do plasma cells produce

A

a group of antibodies all complementary to a specific foreign antigen

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5
Q

Give an example of a pathogen that also causes toxins

A

cholera

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6
Q

What does each toxin molecule also act as

A

an antigen

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7
Q

What are monoclonal antibodies produced by

A

the clones of B cells (plasma cells)

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8
Q

What are monoclonal antibodies

A

antibodies that target the same antigens

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9
Q

What do the cells produced in the clone of B cells become (2 points)

A

1) plasma cells

2) memory cells

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10
Q

What do plasma cells do

A

secrete antibodies usually into blood plasma

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11
Q

How long do plasma cells survive for

A

for a few days

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12
Q

Are B cells present since and what happens when a pathogen is present

A

birth, they multiply

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13
Q

How many antibodies can each plasma cell make every second

A

2000

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14
Q

What do the antibodies secreted by plasma cells do

A

destroy the antigen

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15
Q

What is the production of antibodies and memory cells known as

A

primary immune response

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16
Q

What is the primary immune response

A

the production of antibodies and memory cells

17
Q

What are memory cells responsible for

A

secondary immune response

18
Q

How long do memory cells live for

A

decades

19
Q

Where are memory cells kept

A

circulating in the blood and tissue fluid

20
Q

What are memory cells for

A

future infection

21
Q

What do memory cells provide

A

long-term immunity

22
Q

Describe the role of B cells in the immune response (7 points) - from antigens detected

A

1) surface of antigens taken up by B-cells
2) B-cells present the antigens on their surface
3) Helper T-cells attach to the processes antigens on B-cells and activates the B-cells
4) B-cell is activated to divide by mitosis to give a clone of plasma cells
5) cloned plasma cells produce and secrete the specific antibody that fits the antigen on pathogens surface
6) antibody attaches to antigen on pathogen and destroys it
7) some B cells develop into memory cells

23
Q

How do memory cells respond to infection

A

dividing rapidly into plasma cells that produce antibodies