MITOSIS Flashcards
1
Q
I hope for the best
A
Wha.
2
Q
What is mitosis?
A
Type of cell division in which the 2 daughter cells have the same number of chromosomes and are genetically identical with each other and the parent cell, giving genetic stability
3
Q
Why is mitosis needed?
A
- Growth of tissues
- Repair/replacement of tissues
- Asexual reproduction
- Genetic stability
4
Q
What are the 4 stages of mitosis?
A
A continuous process and is described in 4 stages:
1. Prophase (Purple)
2. Metaphase (Mice)
3. Anaphase (Are)
4. Telophase (Tasty)
5
Q
Explain prophase?
A
- Chromosomes condense (shorten and thicken) and become visible
- Seen as a pair of chromatids joined by a centromere
- So basically the main part is #1 - Centrioles migrate to opposite poles of the cell
- Starts to form a network of protein microtubules called the spindle
-
Nucleolus disappears and prophase ends with the breakdown of the nuclear envelope
Visuals:
- Within we have chromosomes
- Protected by nuclear membrane
- And we have the 2 centrioles on each side; above and below
They rely on cell cytoskeleton for movement
Real visualisation: A bunch of small lines mushed together
6
Q
Explain metaphase?
A
- Chromosomes line up at the equator
- And are attached to the spindle apparatus by their centromere
Visuals:
- Think of it as the basketball lines
- No nuclear membrane btw
- Centromeres above and below
- 4 “spindle fibres” (the lines between centromeres) with each chromosome connected
- From their centromeres
Real visualisation: A bunch of small lines mushed together as a line
7
Q
Explain anaphase?
A
- Centromere splits and sister chromatids separate
- Spindles contract and chromatids pulled
-
To the opposite poles of the cell, centromere first
- Movement of chromatids relies on the cytoskeleton and ATP
Visuals:
- Just like the metaphase
- However the chromosome truly is split
- And are going their separate ways (up/down, if u know u know)
Real visualisation: Very long combs moving far apart
There can also be a late anaphase/early telophase which is small combs far away
8
Q
Explain telophase?
A
- Chromatids reach opposite poles on spindle
- They uncoil and elongate = become chromosomes
- Nuclear membrane forms around each group of chromosomes
- Now there are 2 nuclei
Visuals:
- Think back to prophase visuals but now there’s 2 of them and are splitting
- Centriole will degenerate (the 2 dots above and below)
- Cytoplasm begins to divide
- Cleavage furrow?
Real visualisation: Small lines compactly mushed together as 2 balls