MITOSIS Flashcards

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1
Q

I hope for the best

A

Wha.

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2
Q

What is mitosis?

A

Type of cell division in which the 2 daughter cells have the same number of chromosomes and are genetically identical with each other and the parent cell, giving genetic stability

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3
Q

Why is mitosis needed?

A
  • Growth of tissues
  • Repair/replacement of tissues
  • Asexual reproduction
  • Genetic stability
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4
Q

What are the 4 stages of mitosis?

A

A continuous process and is described in 4 stages:
1. Prophase (Purple)
2. Metaphase (Mice)
3. Anaphase (Are)
4. Telophase (Tasty)

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5
Q

Explain prophase?

A
  1. Chromosomes condense (shorten and thicken) and become visible
  2. Seen as a pair of chromatids joined by a centromere
    - So basically the main part is #1
  3. Centrioles migrate to opposite poles of the cell
  4. Starts to form a network of protein microtubules called the spindle
  5. Nucleolus disappears and prophase ends with the breakdown of the nuclear envelope
    Visuals:
    - Within we have chromosomes
    - Protected by nuclear membrane
    - And we have the 2 centrioles on each side; above and below
    They rely on cell cytoskeleton for movement
    Real visualisation: A bunch of small lines mushed together
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6
Q

Explain metaphase?

A
  1. Chromosomes line up at the equator
  2. And are attached to the spindle apparatus by their centromere
    Visuals:
    - Think of it as the basketball lines
    - No nuclear membrane btw
    - Centromeres above and below
    - 4 “spindle fibres” (the lines between centromeres) with each chromosome connected
    - From their centromeres
    Real visualisation: A bunch of small lines mushed together as a line
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7
Q

Explain anaphase?

A
  1. Centromere splits and sister chromatids separate
  2. Spindles contract and chromatids pulled
  3. To the opposite poles of the cell, centromere first
    - Movement of chromatids relies on the cytoskeleton and ATP
    Visuals:
    - Just like the metaphase
    - However the chromosome truly is split
    - And are going their separate ways (up/down, if u know u know)
    Real visualisation: Very long combs moving far apart
    There can also be a late anaphase/early telophase which is small combs far away
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8
Q

Explain telophase?

A
  1. Chromatids reach opposite poles on spindle
  2. They uncoil and elongate = become chromosomes
  3. Nuclear membrane forms around each group of chromosomes
  4. Now there are 2 nuclei
    Visuals:
    - Think back to prophase visuals but now there’s 2 of them and are splitting
    - Centriole will degenerate (the 2 dots above and below)
    - Cytoplasm begins to divide
    - Cleavage furrow?
    Real visualisation: Small lines compactly mushed together as 2 balls
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