Mitosis Flashcards

1
Q

What divides via binary fission?

A

Prokaryotes
Mitochondria
Chloroplasts

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2
Q

What divides via mitosis?

A

Somatic/body cell eukaryotes

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3
Q

What divides via meiosis?

A

Gamate/germs/sexual cells eukaryotes

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4
Q

What shape chromosome do prokaryotes have in binary fission?

A

Circular

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5
Q

DNA polymerase is used in?

A

Binary fission

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6
Q

What occurs in binary fission?

A

New chromosomes move to opposite ends of the cell.
Septum forms to divide cells

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7
Q

DNA + proteins

A

Chromatin

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8
Q

What is DNA wrapped around and why?

A

Histone to keep DNA organized

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9
Q

DNA and histone structure?

A

Eight histone proteins spaced 200 nucleotides apart

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10
Q

DNA that is not expressed/transcribed. Does not code for proteins

A

Heterochromatin

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11
Q

DNA that is expressed/transcribed. Codes for proteins or genes

A

Euchromatin 

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12
Q

Similar genes/alleles how long to DNA molecules

A

Homologous pair

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13
Q

Mitosis process

A

All chromosomes are replicated. Single division creates to 2N cells from 1 2N cell

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14
Q

What cells do not perform mitosis?

A

Gametes and red blood cells

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15
Q

Shows 22 pairs of homologous chromosomes, one X, one Y condensed during mitosis

A

Karyotype

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16
Q

5 phases of cell cycle

A

G1
S
G2
M
C

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17
Q

What 3 phases are included in interphase?

A

G1- Cell growth
S- DNA replication
G2- Chromosomes condense and organelles develop

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18
Q

What find sister chromatids together

A

Cohesion proteins

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19
Q

What activates proteins that illuminates the cohesion to separate sister chromatids?

A

Anaphase promoting

20
Q

What region do the sister chromatids share?

A

Centromere

21
Q

 Connect centromere to microtubules

A

 Kinetochore proteins

22
Q

Where are microtubules organized?

A

Centrioles at each pole of cell

23
Q

5 phases of mitosis

A

Prophase
Prometaphase/ Metaphase
Anaphase
Telophase
Cytokinesis 

24
Q

Prophase

A

Chromosomes condense
Centrioles move to each pole
Spindle apparatus assembles (microtubules)
Nuclear envelope dissolves

25
Prometaphase
Chromosomes attached to spindle apparatus by kinetochores Second set of microtubules formed from centrioles to kinetochores Microtubule begin to pull each chromosome toward center of cell
26
Metaphase
Microtubules pull chromosomes to align them at center of cell  sister chromatids lineup with centromere‘s on metaphase plate/equator
27
Anaphase
Remove cohesion using anaphase promoting complex to allow chromatids to separate Microtubules contract pulling sister chromatids towards poles
28
Telophase
Spindle apparatus disassembles Nuclear envelope forms around each set of sister chromatids Chromosomes begin uncoiling Nucleolus reappears around each nucleus
29
What is the term for the shape of the spindle apparatus?
Aster
30
Cytokinesis
Cleavage of cell membranes into halves
31
What is responsible for cytokinesis in animals?
Actin filaments
32
What is responsible for cytokinesis in plants?
Cell plate
33
How does cytokinesis occur in fungi/Protists?
Division of nucleolus
34
Proteins produced during cell cycle
Cyclines
35
Enzymes that drive cell cycle. Activate via phosphorylation when cyclin bonds.
Cycling dependent kinases
36
Three checkpoints
1) G1/S 2) G2/M  3) Late metaphase/spindle
37
G1/S checkpoint
Cell decides to divide. G1 cyclin + Gcd2 = G1/s Cdk
38
G2/M checkpoint
Cell commits to mitosis
39
Late metaphase/spindle checkpoint
Cell ensures chromosomes are attached to spindle before to dividing. Anaphase promoting complex proteins that remove cohesion between chromatids.
40
Trigger intracellular signals that inhibit cell division
Growth factors
41
How is cancer cause?
Cell cycle loses control leading to unregulated, excess cell division
42
What is an example of a growth factor?
Platelet derived growth factor (heal wound)
43
Prevent division of mutated cells
Tumor suppressor genes
44
Code for growth factor or signal transduction proteins. Promote normal cell division.
Proto oncogenes
45
Proto oncogene mutation leads to?
Mutated proto oncogene create oncogenes which caused excess cell division Cause cancer when introduced to a new cell
46
How do you tell the difference between mitosis and meiosis?
During metaphase mitosis- diploid number of chromosomes  meiosis- haploid number of chromosomes