Mitochondria Flashcards
The ______ are the usual source of energy for the cell
high energy bonds in ATP
The primary sources of ATP in animal cells
fatty acids and glucose
the initial stages of glucose degradation occur
in the cytosol
oxidative phosphorylation: what it is and where it occurs
the terminal stages that involve oxygen that occurs in the mitochondria
endosymbiont hypothesis
inner mitochondria membrane is derived from bacteria, while the outer membrane would be derived from eukaryotic cell
mitochondria arose early in the evolution of eukaryotic cells by
endocytosis of bacteria capable of oxidative phosphorylation
The outer membrane of mitochondria is _______, and the inner membrane is ______ permeable and contains most of the machinery required for _______
- semi-permeable
- much less
- oxidative phosphorylation
the surface of the inner membrane is greatly increased by
-a large number of infoldings known as cristae
The central space of the mitochondria =
matrix
mitochondrial proteins are synthesized in the _______ and imported via _______
- cytosol
- TOM (translocase of outer membrane) and TIM (translocase of inner membrane) complexes
transport through TOM is _______ while transport through TIM is _______
- passive
- ATP-dependent
Fusion
- plays a key role in repairing damaged mitochondria
- dependent on GTPase Mfn and OPA1
fission
- required for mitophagy
- dependent on GTPase Fis1 and Drp
During respiration in mitochondria,
electrons are released from NADH and transferred to O2 to form H2O
what generates the proton concentration gradient?
protons from the mitochondrial matrix are pumped across the inner membrane
