Mistakes Flashcards
What is the approximate width of a membrane
7um
Colour change in buret test
blue to lilic purple
Bind between two sugars
glycosdic
Describe a test that the student could carry out to discover whether this sample contained a lipid.
Add mix with ethanol, , then add water
Difference in structure of triglyercide and phospholipid
P-lipids - 2 fatty acids - P replaces one of the fatty acids 2 ester bonds not 3 polar/hydrophilic head
Describe how malonate inhibits the enzyme. You may use the space below for a diagram to help your answer.
(in isn’t permanent)
similar shape to substrate inhibitor complementary to active site blocks active site for limite dite / reversible prevents es complex forming no products formed
Explain what would happen to the reaction if the concentration of succinate was increased relative to the concentration of malonate.
greater chance of substrate binding with site
more es substrates- products
reaction rate increases
Use the diagram to explain why this drug is effective in the treatment of gout.
(diagram of drug and substrate that are similar )
similar shape to drug –> drug fits active site –>competes-competitive inhibitor
less acid formed
Cells under ciliated epithelium in bronchiole
smooth muscle (look like flat eyes)
Blobs in oesophagus
Blood vessel (bRANCHED)
What is function of ciliated epithelium
cilia beat, mucus moved back up bronchiole, protective
one similarity between hair like structure in intestine and ciliated epithelial
Both columnar epithelial
one Difference between hair like structure in intestine and ciliated epithelial
microvilli vs cilia
Glycosidic bonds between what and what is removed
monosachride molecules and water
Colour change in benefits solution
blue to red brown preicipate
how can bond be broken chemically to break apart a non reducing sugar
hydrolyse by heating ( dilute HCL)
Explain how structure of stomach walls and oesophagus wall are related to the functions oft these organs
oesophagus - Thick mucusa /epithelial layer, outer cells flatted
- withstands abrasion from semi solid food
oesophagus food from mouth to stomach
stomach = site of digestion - protein
food churned with acid and endopeptidases
thick mucose / gastric pits = gastric juices
mucus secretion - protection
muscular wall = 3 layers muscles - churn and break up food
describe the function of the up going up in ileum
Absorbs/ transports triglycerides
Advantage of having muscle in villi
allow movement of villi - greater contact with food in lumen for digestion /absorption
How is the inner membrane of the mitochondria adapted to its function
inner membrane (folded)
increases surface area to form cristae
mitochondria site of respiration /ATP production
greater SA - greater ATP production
Comparison of prokaryotic and eukaryotic
Ribosomes present : yes yes
cell diameter usually more than 20 um = eu= yes , pro= no
cells may contain plasmid- pro = yes, eu - no
dna combined with protein into chromosomes - pro -= yes , eu = yes
nuclear membrane present - pro - no, eu - yes
cell wall always present , pro - yes , eu - no
Using the information given above, suggest why the COX enzyme is found attached to the inner surface of the endoplasmic reticulum.
idea th
at arachindate is substrate
p lipid source in membrane
SER for lipid/steroid synth?/transport
prostaglandins can be transported /stored
AVP- separate from other cellular reactions
prostaglandins isolated in ER
P lipids from other membranes unaffected
Describe the effect of low temperature ,such as 5 oc , on enzyme action
Decrease reaction rate ref. kinetic energy molecules moving more slowly fewer collisions fewer es complexes reversibel - Enzyme not dnatured
How many something be kept as a control
contains all substances except one
projections on CELL
microvilli
correct term for outer layer
EPethITHIAL LAYER
(ii) Explain how transport of sugars into cells lining the intestine (lines8-9) leads to water being absorbed.
sugar absorbed, fluid in gut becomes less negative than that of blood, water passes into blood by osmosis
Plasma membranes that have been isolated from red blood cells are not contaminated by internal cell membranes.
Explain why.
no internal membrane bound organelles
Explain why red blood cells that do not contain spectrin burst more quickly when put into distilled water.
spectrum strengthens the membrane, cells swell when place in distilled water (osmosis) - weaker membrane rupture more easily
Suggest what caused the sudden increase in the rate of diffusion at 40 °C.
break down of bonding in membrane, (due to kinetic energy ), proteins denature
Describe the function of ribosomes
site of protein synthesis
where genetic code is used to build protein
Describe the function of lysosomes
protein digestion (enzyme )
digest warn out organelles
in white blood cells- phagocytosis
digest cell when dies
Describe the function of nuclear pres
to allow substances into and out of cell
connects nucleus to cytoplasm via MRNA
Explain why the change in mass was given as a percentage change.
allows accurate comparison
graph accuracy
what is the point called where there is no change in mass ( due to concentration of something )
isotonic point
Use your knowledge of enzymes to explain how cyanide stops the activity of cytochrome oxidase.
binds to enzyme at point away from the active site
changes 3 o structure
alters active site
so ES complex can’t for m
Suggest what type of substance would cause the antibody to attach only to cancer cells.
protein
Explain how this method would kill cancer cells, but not other cells.
antibody only bids to receptor protein on cancer cells
antibody has enzyme attached
linemen injected will only be broken down at cancer cell sites
cynaide released to cancer cells
With reference to Fig. 2.1, describe the events occurring at the stages labelled 1 to 4. (order to events for secretion of insulin )
glucose , respired / phosphorylated / metabolised ,
to produce ATP ;
2 ATP , blocks / closes , potassium ion channel(s) and
potassium ions / K+ ,
build up (inside cell) / cannot leave ;
3 (voltage-gated) calcium ion / Ca2+ , channels open and
calcium ions / Ca2+ , enter (cell by diffusion) ;
4 (more) calcium ions / Ca2+ , resulting in , movement of vesicles to membrane /
exocytosis / described ;
After the initial release of insulin from the beta cell, insulin secretion continues even when there is no further glucose intake.
Suggest and explain why the cell continues to secrete insulin.
1 (continues to be secreted) as long as
blood / plasma , glucose (concentration) ,
remains high / is higher than normal ;
2 (sufficient) ATP is still present
and so K+ channels remain closed ;
3 (exocytosis) still being triggered by ,
calcium ions / Ca2+;