MISCELLANEOUS TOPICS Flashcards
Cytochromes are useful in which reactions?
A. Oxidation reduction
B. Transamination
C. Decarboxylation
D. Hydrolysis
E. Deamination
A. Oxidation reduction
A necessary precursor of visual pigment is:
A. Retinal
B. Retinol
C. Ergosterol
D. Cholecalciferol
A. Retinal
Which of the following terms describes a reduced number of platelets?
A. Thrombocytopenia
B. Leukopenia
C. Leukocytosis
D. Thrombophlebitis
E. Thrombocytosis
A. Thrombocytopenia
Tay-Sach disease is associated with an inborn error of metabolism involving a specific enzyme which normally degrades a particular molecule in the gray matter. This enzyme acts on which of the following?
A. Polysaccharides
B. Acylglycerols
C. Gangliosides
D. Fatty acids
E. Proteins
C. Gangliosides
The most biologically important physiochemical property of connective tissue which is regulated by its mucopolysaccharide molecules is:
A. Viscosity
B. Buffering capacity
C. Solubility in dilute acids
D. Supersaturation with calcium ions
A. Viscosity
Which of the following compounds is NOT involved in coagulation of blood?
A. Fe+2
B. Ca+2
C. Prothrombin
D. Fibrinogen
E. Thromboplastin
A. Fe+2
Which of the following ions is involved in blood clotting?
A. Iron
B. Sodium
C. Calcium
D. Potassium
C. Calcium
A deficiency in vitamin K would affect blood clotting chiefly by:
A. decreasing prothrombin production
B. preventing the contraction of the clot
C. preventing the reaction of thrombin with fibrinogen
D. preventing the conversion of fibrinogen to fibrin
E. preventing the conversion of prothrombin to thrombin
A. decreasing prothrombin production
Which of the following represents the normal substrate of thrombin?
A. Fibrin
B. Thrombospondin
C. Prothrombin
D. Thromboplastin
E. Fibrinogen
E. Fibrinogen
Platelets play an important role in hemostasis. Which of the following describes this role?
A. They convert fibrinogen to fibrin
B. They agglutinate and plug small, ruptured vessels
C. They initiate fibrinolysis in thrombosis
D. They supply fibrin stabilizing factor
E. They supply proconvertin for thromboplastin activation
B. They agglutinate and plug small, ruptured vessels
Administration of heparin to a human results in symptoms similar to vitamin K deficiency in that both conditions result in:
A. release of lipoprotein lipase to the blood and rapid clearance of chylomicrons
B. and increase in bleeding time due to lack of thrombin formation
C. retardation of fibrinogen synthesis by the liver
D. elevated non-esterified fatty acids which chelate serum calcium, thus retarding blood clotting
B. and increase in bleeding time due to lack of thrombin formation
The unique amino acid composition of collagen is reflected in the high content of:
A. Valine, threonine, and lysine
B. Desmosine, glycine, and proline
C. Cysteine, hydroxylysine, and proline
D. Cysteine, tyrosine, and phenylalanine
E. Glycine, proline, and hydroxyproline
E. Glycine, proline, and hydroxyproline
Which of the following is MOST likely to promote depolymerization of extracellular matrix?
A. Cortisone
B. Collagenase
C. Chymotrypsin
D. Hyaluronidase
D. Hyaluronidase
Which of the following vitamins is essential for the normal elaboration and maintenance of bone matrix, cartilage, and dentin?
A. Niacin
B. Vitamin E
C. Ascorbic acid
D. Pantothenic acid
C. Ascorbic acid
Which of the following tests is specific for the presence of free amino acid groups?
A. Biuret tests
B. Hopkin’s Cole test
C. Ninhydrin test
D. Xanthoproteic test
E. Sakaguchi test
C. Ninhydrin test
