Miscellaneous Bone Lesions

Question 1

most common cause of dwarfism, which is a congenital hereditary disease of failure of endochondral bone formation

Answer 1

achondroplasia

Question 2

more profoundly affected in achondroplasia (2)

Answer 2

femurs and humeri

Question 3

characteristic finding in this condition is narrowing of interpedicular distances in a caudal direction

Answer 3

achondroplasia

Question 4

lack of blood supply with subsequent bone death and ensuing bony collapse in an articular surface

Answer 4

avascular necrosis

Question 5

manifested by clubbing of fingers and periostitis, usually in the upper and lower extremity, which might or might not be associated with bone pain

Answer 5

hypertrophic osteoarthropathy

Question 6

hypertrophic osteoarthropathy are most commonly seen in patients with

Answer 6

lung cancer or other lung disease

Question 7

rare idiopathic disorder characterized by thickened cortical new bone that accumlates near the ends of long bones, usually only on one side of the bone and has an appearance likened to “dripping candle wax”

Answer 7

melorheostosis

Question 8

group of inherited lysosomal storage diseases characterized by the abnormal accumulation of various mucopolysaccharides such as keratan sulfate and heparan sulfate

Answer 8

mucopolysaccharidoses

Question 9

mucopolysaccharidoses include (2)

Answer 9

morquio (keratan sulfate) and Hurler and Hunter (heparan sulfate)

Question 10

those with mucopolysaccharidoses have what appearance

Answer 10

short stature, from shortened spines

Question 11

mucopolysaccharidoses that has platyspondyly in the spine with central anterior projection of beak off the vertebral body

Answer 11

Morquio

Question 12

mucopolysaccharidoses that has platyspondyly with a beak that is anteroinferiorly positioned

Answer 12

Hurler and Hunter

Question 13

pelvic appearance of wide, flared iliac wings and broad femoral necks are seen in (2)

Answer 13

mucopolysaccharidoses and achondroplasia

Question 14

it has a characteristic finding of pointed proximal fifth metacarpal base that has a notched appearance to the ulnar aspect

Answer 14

mucopolysaccharidoses

Question 15

multiple osteochondromas or exostoses

Answer 15

diaphyseal aclasis

Question 16

cartilage-capped bone outgrowth that may be pedunculated or sessile in appearance

Answer 16

osteochondroma

Question 17

widened diameter of bone

Answer 17

undertubulation

Question 18

in multiple hereditary exostoses, malignant degeneration are commonly seen in what lesions

Answer 18

axial situated lesions

Question 19

painful lesions that occurs almost exlusively in patients less than 30 and is treated successfully with surgical excision or thermal ablation. it is a cortically bases sclerotic lesions in a long bone that has a small lucency within it that is called a nidus

Answer 19

osteoid osteoma

Question 20

what causes pain in osteoid osteoma

Answer 20

nidus and the surrounding sclerosis

Question 21

5 conditions that present with periostitis without underlyng bony lesion

Answer 21

• trauma,
• hypertrophic pulmonary osteoarthropathy,
• venous stasis,
• thryoid acropachy,
• pachydermoperiostosis

TV-HPT

Question 22

how to differentiate osteoid osteoma from osteomyelitis

Answer 22

the nidus in osteoid osteoma is vascular, it avidly accumulates bone scanning agents and demonstrates double density sign. osteomyelitis has an avascular central photopenic area

Question 23

also known as osteopathia striata, manifested by multiple 2 - 3 mm thick linear bands of sclerotic bone aligned parallel to the long axis of a bone. usually affects long bones and asymptomatic

Answer 23

Voorhoeve disease

vOOrhOeve disease = OsteOpathia striata

Question 24

is a hereditary, asymptomatoc disorder that is usually an incidental finding of multiple small (3 to 10 mm) sclerotic bony densities affecting primarily the ends of long bones and pelvis. it has no clinical significance but can be confused for diffuse osteoblastic metastases

Answer 24

osteopoikilosis

osteopoikilosis = poiko = polkadot = multiple small sclerotic bony densities

Question 25

rare familial disease that is manifested by thickening of the skin of the extremities and face, clubbing of the fingers and widespread periostitis. occassionally painful

Answer 25

pachydermoperiostosis

pachy = thickening; dermo = skin; perio =periostitis

Question 26

in sarcoidosis of MSK, what is particularly involved

Answer 26

hands (most common), with spine and long bones

Question 27

causes lacelike pattern of bony destruction in the hands

Answer 27

sarcoidosis

Question 28

1. an idiopathic process that begins with a painful hip with no underlying disorder or other findings other than osteoporosis which is limited to the painful hip. Painful bone marrow edema has been reported in the hip, knee, distal clavicle, and ankle.
2. A similar process occurs in the knee. It is seen most commonly in the medial condyle but can occur laterally or in the proximal tibia adjacent to the joint.
3. It can occur in several different locations over time or simultaneously and then is called

Answer 28

transient osteoporosis of the hip / idiopathic transient osteoporosis of the hip (ITOH)

painful bone marrow syndrome

regional migratory osteoporosis.