Benign Lucent Bone lesions Flashcards

1
Q

Enumerate FEGNOMASHIC

A

Fibrous dysplasia, Enchondroma, Eosinophilic granuloma, Giant cell tumor, Nonossifying fibroma, Osteoblastoma, Metastatic disease and Myeloma, Aneurysmal Bone Cyst, Solitary bone cyst, Hyperparathyroidism (Brown tumors), Hemangiomas, Infection, Chondroblastoma, Chondromyxoid fibroma

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2
Q

fibrous dysplasia can be seen at what age

A

any age

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3
Q

discriminator for fibrous dysplasia

A

no periosteal reaction

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4
Q

2 discriminator for enchondroma

A

calcification present (except in phalanges), painless (no periostitis)

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5
Q

discriminator for eosinophilic granuloma

A

younger than 30

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6
Q

4 discriminator for giant cell tumor

A
  • closed physes,
  • abuts the articular surface (in long bones),
  • well defined with a nonsclerotic margin (in long bones),
  • eccentric
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7
Q

2 discriminator for nonossifying fibroma

A

younger than age 30, painless (no periostitis)

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8
Q

discriminator for osteoblastoma

A

mentioned when ABC is mentioned (especially in the posterior elements of the spine)

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9
Q

discriminator for metastatic diseases and myeloma

A

older than age 40

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10
Q

2 discriminator for aneurysmal bone cyst

A

expansile, younger than age 30

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11
Q

2 discriminator for solitary bone cyst

A

central, younger than age 30

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12
Q

2 discriminator for hyperparathyroidism (brown tumor)

A

must have other evidence of HPT, rare, may be multiple

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13
Q

discriminator for infection

A

always mention

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14
Q

2 discriminator for chondroblastoma

A

younger than age 30, epipiphyseal

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15
Q

discriminator for chondromyxoid fibroma

A

no calcified matrix

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16
Q

most common form of fibrous dysplasia

A

monostotic

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17
Q

4 predilection of fibrous dysplasia

A

PPRS

  • pelvis,
  • proximal femur,
  • ribs and
  • skull
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18
Q

typical appearance of fibrous dysplasia in the ribs

A

expansile, lytic appearance in posterior ribs, sclerotic appearance in the anterior ribs

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19
Q

classic description of fibrous dysplasia

A

ground glass or smoky matrix

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20
Q

lesion that resembles fibrous dysplasia in the tibia

A

adamantinoma

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21
Q

it is a malignant tumor that radiographically and histologically resembles fibrous dysplasia

A

adamantinoma

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22
Q

adamantinoma is common in what 2 parts of the body

A

tibia and jaw

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23
Q

polyostotic fibrous dysplasia occassionally occurs in association with cafe au lait spots on the skin and precocious puberty

A

McCune Albright syndrome

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24
Q

McCune Albright syndrome is commonly unilateral or bilateral

A

unilateral, affecting 1/2 of the body

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25
Q

multiple lesions of fibrous dysplasia in the jaw is called

A

cherubism

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26
Q

true or false: jaw lesions in cherubisms regress in adulthood

A

true

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27
Q

most common benign lytic lesion in the phalanges. invariably contain calcified chondroid matrix except when in the phalanges of the hands and feet

A

echondromas

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28
Q

how to differentiate bone infarct from enchondroma

A

infarct usually has a well-defined, densely sclerotic serpiginous border, enchondroma does not. enchondroma often causes mild endosteal scalloping

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29
Q

multiple enchondromas has been termed

A

Ollier disease

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30
Q

presence of multiple enchondromas associated with soft tissue hemangiomas is known as

A

Maffucci syndrome

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31
Q

true or false: Maffucci syndrome carries a high risk of malignant degeneration than Ollier disease

A

true

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32
Q

typical appearance of enchondroma other than in the phalanges

A

stippled punctate calcification typical of chondroid matrix

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33
Q

also known as langerhans cell histiocytosis; is the most common and least severe form of LCH, with the other forms being Letterer-Siwe disease and Hand-Schuller-Christian disease

A

Eosinophilic granuloma

34
Q

eosinophilic granuloma is commonly of what type

A

monostotic

35
Q

bony sequestrum is typical of osteomyelitis, but can also be seen in what benign lesion especially in young patients

A

eosinophilic granuloma

36
Q

aside from osteomyelitis and EG, bony sequestrum can also be seen in (3)

A

lymphoma, fibrosarcoma, osteoid osteoma may simulate sequestrum if it shows calcification

FLO

37
Q

uncommon tumor found almost exclusively in adults in the ends of long bones and in flat bones

A

Giant cell tumor

38
Q

giant cell tumor must be at what part of the bone

A

epiphyseal and abut the articular surface

39
Q

very helpful finding in GCT; not applicable to flat bones, such as pelvis and calcaneus

A

sharply defined zone of transition (border) that is not sclerotic

40
Q

3 locations where giant cell tumors often occur

A

sacrum, pelvis and calcaneus

41
Q

also called fibroxanthoma, is probably the most common bone lesion encountered by radiologists

A

non-ossifying fibroma

42
Q

benign, asymptomatic lesions that typically occur in the metaphysis of a long bone, emanating from the cortex

A

non ossifying fibroma

43
Q

classic appearance of NOF

A

sclerotic border, scalloped and slightly expansile

44
Q

true or false: NOFs routinely “heal” with sclerosis and eventually disappear, usually around ages of 20 to 30 years

A

true

45
Q

NOFs may appear hot on a radionuclide bone scan because there is

A

osteoblastic activity

46
Q

true or false: NOFs can occasionally get quite large, therefore, growth or change in size should not alter the diagnosis

A

true

47
Q

NOFs are most commonly seen in what part

A

knee

48
Q

two appearance of osteoblastoma

A

looks like large osteoid osteoma and are often called giant osteoid osteomas, primarily sclerotic lesions due to reactive bone formation and do not resemble bubbly lucent lesions; simulates ABCs, often having a soap bubble appearance

49
Q

common location of osteoblastomas

A

posterior elements of vertebral bodies

50
Q

appearance of calcifications in osteoblastomas

A

speckled calcifications

51
Q

metastatic disease should be considered for any lytic lesion-benign or aggressive in appearance- in a patient of what age

A

more than 40 years of age

52
Q

diffuse permeative process in the skeleton

A

myeloma

53
Q

bubbly, lytic bone lesions of myeloma are more correctly called

A

plasmacytomas

54
Q

in general, lytic expansile metastatic diseases tend to come from

A

thyroid and renal tumors

55
Q

metastatic lesion that is said to always be lytic is

A

renal cell carcinoma

56
Q

characteristic appearance of plasmacytoma involving vertebral body on CT and MRI

A

“mini-brain”

57
Q

common location for plasmacytoma aside from the vertebral body

A

ilium

58
Q

aneurysmal bone cysts virtually always presents as (2)

A

expansile; also fluid-fluid levels

59
Q

secondary ABCs have been said to occur with

A

giant cell tumors, osteosarcomas and many other lesions

60
Q

said to be pathognomonic for a unicameral bone cyst

A

fallen fragment sign

61
Q

only lesion in FEGNOMASHIC that is always central in location

A

solitary/unicameral bone cyst

62
Q

2/3 to 3/4 of these lesions occur in the proximal humerus and proximal femur

A

solitary/unicameral bone cyst

63
Q

solitary bone cyst pattern of growth

A

begin at the physeal plate in long bones and grow into the shaft of the bone

PP-S

64
Q

common location of solitary bone cyst in the calcaneus

A

inferior surface of the calcaneus

65
Q

pathognomonic finding for HPT

A

subperiosteal bone resorption

66
Q

4 common location of HPT

A
  • radial aspect of the middle phalanges,
  • medial aspect of proximal tibia,
  • distal clavicles and
  • sacroiliac joints
67
Q

also known as cystic angiomatosis or cystic lymphangiomatosis

A

hemangiomas

68
Q

massive osteolysis or disappearing bone disease

A

Gorham disease

69
Q

focus of devitalized bone that does not have a blood supply and will not be effectively treated with parenteral medication

A

sequestrum

70
Q

abscess collection in the proximal humerus

A

Brodie’s abscess

71
Q

rare lesions but are among the easiest lesions for radiologists to deal with because they occur in the epiphyses

A

chondroblastomas

72
Q

3 differential diagnosis of a lytic lesion in the epiphysis of a patient less than 30 years of age are:

A

infection,chondroblastoma, GCT

73
Q

four disease process that presents with subchondral cyst or geode

A
  • degenerative joint disease,
  • RA,
  • calcium pyrophosphate dihydrate crystal disposition disease or pseudogout and
  • avascular necrosis
74
Q

basically resembles NOFs but can occur at any age

A

chondromyxoid fibroma

75
Q

5 lesions in patients younger than 30 years of age

A

E-SCAN

EG, 
ABC, 
NOF, 
chondroblastoma, 
solitary bone cyst
76
Q

4 lesions that have no pain or periostitis

A

FENS

fibrous dysplasia,
enchondroma,
NOF,
solitary bone cyst

77
Q

4 epiphyseal lesions

A

IG-CG

  • infection,
  • GCT,
  • chondroblastoma,
  • Geode
78
Q

5 differential for rib lesions

A

(FAMEE)

  • fibrous dysplasia,
  • ABC,
  • metastatic disease and myeloma,
  • enchondroma and
  • EG
79
Q

7 multiple lesions

A

FEEMHHI

  • fibrous dysplasia,
  • EG,
  • enchondroma,
  • metastatic disease and myeloma,
  • HPT,
  • hemangiomas,
  • infection
80
Q

difference between epiphyses and apophyses

A

epiphyses contribute to the length of bone, whereas apophyses serve as tendon and ligament attachment sites

81
Q

sclerotic focus identified in a 20 to 40 year old patient, especially if asymptomatic, incidental finding, the following lesions should be considered (6):

A

AB-SC-EN

  • NOF,
  • EG,
  • ABC,
  • solitary
  • bone cyst and
  • chondroblastoma