Miscellaneous bacteria Flashcards

1
Q

A stain that is used to visualize Mycoplasma

A

Acridine orange

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2
Q

Rickettsialpox

A

R. akari

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3
Q

Boutonneuse fever

A

R. conorii

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4
Q

Scrub typhus

A

R. tsutsugamushi

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5
Q

Arthritis usually appears at what stage of lyme disease

A

Stage 3

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6
Q

Eaton agent

A

M. pneumoniae

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7
Q

Which of the following C. trachomatis serotype is capable of causing nongonococcal urethritis

A

Serotype D

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8
Q

R. rickettsi falls under which group?

A

Spotted fever group

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9
Q

Granulomatous lesions n syphilis appears at which stage?

A

Tertiary

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10
Q

Bartonella spp. Lives on which type of cell?

A

RBC

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11
Q

TWAR stain

A

C. pneumoniae

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12
Q

Causative agent of murine typhus

A

R. typhi

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13
Q

Rapid plasma regain is used to detect which disease

A

Syphilis

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14
Q

Causative agent of relapsing fever

A

Borrelia recurrentis

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15
Q

Causative agent of lyme disease

A

Borrelia burgdorferi

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16
Q

Spirochaetaceae has two genus

A
  • borrelia
  • treponema
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17
Q

Known as periplasmic flagella - responsible for motility

A

Fibrils

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18
Q

Tightly coiled, thin, flexible spirochetes with hooked ends

A

Leptospira

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19
Q

What is the respiratory requirement of leptospira?

A

Obligate aerobe

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20
Q

What is the incubation period for leptospirosis?

A

10-12 days

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21
Q

What are the principal animal reservoir?

A

Dogs, rats, and other rodents

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22
Q

Mode of transmission: leptospirosis

A
  1. Direct contact with urine of carriers
  2. Indirect by contact with bodies of water contaminated with the urine of carriers
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23
Q

Severe systemic disease. Includes renal failure, hepatic failure, and intravascular disease and can result in death

A

Weil disease

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24
Q

What is the prophylaxis for leptospirosis?

A

Doxycycline

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25
Q

Less tightly coiled. All pathogenic species are arthropod-borne

A

Borrelia

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26
Q

What are the two types of relapsing fever?

A
  • endemic relapsing fever
  • epidemic relapsing fever
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27
Q

Tick-borne; ornithodoros

A

Endemic relapsing fever

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28
Q

Louse-borne; pediculus humanus

A

Epidemic relapsing fever

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29
Q

What is the specimen for borrelia and leptospira?

A

Blood

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30
Q

What are the stain used in borrelia?

A

Giemsa or Wright stained blood smear

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31
Q

Borrelia us cultivated using

A

Kelly medium

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32
Q

Transmitted via the bite of infected lxodes ticks

A

Lyme disease

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33
Q

Focus on the cardiac, musculoskeletal, neurologic system

A

Stage 3 or late manifestation or late persistent infections

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34
Q

exhibit erythema migrans classic skin lesion that is normally found at the site of the tick bite

A

Stage 1

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35
Q

Secondary skin lesions, migratory joint and bone pain, alarming neurologic and cardiac pathology, splenomegalt, severe malaise and fatigue

A

Stage 2 or early disseminated

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36
Q

It begins as a red macule and expands to form large annular erythema with partial central clearing

A

Stage 1

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37
Q

Tightly twisted spiral bacteria. Difficult to visualize using bright field microscope

A

Treponema

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38
Q

Culturable

A

Leptospira

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39
Q

Stain easily and can visualize using bright field microscope

A

Borrelia

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40
Q

Pinta

A

Treponema carateum

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41
Q

Yaws

A

T. pallidum subsp. pertenue

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42
Q

Endemic syphilis (bejel)

A

Treponema pallidum subsp. endemicum

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43
Q

Syphilis

A

Treponema pallidum subsp. pallidum

44
Q

What is the mode of transmission in treponema?

A

Direct sexual contact

45
Q

Artificial medium used in leptospira

A
  • Fletcher’s semisolid
  • Stuart liquid
  • Ellinghausen-McCullough-Johnson-Harris semisolid media or EMJH
46
Q

Leptospira can be visualize using

A

Dark field, phase contrast, and immunofluorescent microscopy

47
Q

Nongenital contact with a lesion

A

On the lip

48
Q

Transplacental transmission

A

Transmission to fetus (CONGENITAL SYPHILIS)

49
Q

Manifested by skin lesion known as hard chancre.
Single erythematous lesion that is nontender but firm, with a clean surface and raised border

A

Primary stage of syphilis

50
Q

Condyloma lata - macular, papular, follicular, papulosquamous

A

Seconda stage of syphilis

51
Q

Asymptomatic stage

2 years to 40 years

A

Latent state (inactive stage)

52
Q

Development of granulomatous lesions - gummas

Fatal

A

Tertiary stage of syphilis (late syphilis)

53
Q

What are the four serological tests

A
  • RPR - rapud plasma reagin
  • VDRL - venereal disease research laboratory
  • FTA-ABS test
  • Hemagglutinin test
54
Q

Commonly used serological test

A

RPR - rapid plasma reagin

55
Q

Primary method used for the laboratory diagnosis of syphilis

A

SEROLOGY

56
Q

Smallest self-replicating organisms in nature.

A

Mycoplasma

57
Q

Mycoplasma is resistant to which antibiotic?

A

Penicillin and cephalosporin

58
Q

Which organisms are rapid growing?

A

Mycoplasma hominis and Ureaplasma spp

59
Q

Which specie is slow growing organism?

A

Mycoplasma pneumoniae

60
Q

Colonies wity slightly raised centers giving the classic fried egg appearance

A

Mycoplasma spp

61
Q

What are the mode of transmission of mycoplasma?

A
  • direct sexual contact
  • vertical transmission
  • respiratory secretions or fomites
62
Q

Requires urea

A

Ureaplasma

63
Q

Requires glucose

A

Mycoplasma pneumoniae and mycoplasma genitalium

64
Q

Requires arginine

A

Mycoplasma hominis

65
Q

Also known as pleuropneumonia like organism

A

Mycoplasma pneumoniae

66
Q

Other term for mycoplasma pneumoniae

A

Walking pneumoniae of asymptomatic pneumoniae

67
Q

Causes non-gonococcal urethritis or vaginitis

A

Mycoplasma hominis and mycoplasma urealyticum

68
Q

Can be transmitted to the ferus ar delivery and have been recovered from rhe CSF

A

Mycoplasma hominis and mycoplasma urealyticum

69
Q

Only species that can grow on SBA and CAP

A

Mycoplasma hominis

70
Q

Ability to metabolize urea to form ammonia

A

Mycoplasma urealyticum

71
Q

Colonies of chlamydia remains

A

Colorless

72
Q

Causing trachoma. Eye infection that can lead to blindness

A

Serotype A, B, C

73
Q

Vaginitis nongonococcal urethritis, epididymitus and prostatitis.
Also causes conjunctivitis

A

Serotype D to K

74
Q

Risk favtor for Guillain-Barre syndrome

A

Chlamydophila pneumoniae

75
Q

What test is used to differentiate chlamydophila trachomatis?

A

Sulfonamide susceptibility test

76
Q

What is susceptible in sulfonamide susceptibility test?

A

Chlamydophila psittaci

77
Q

Causative agent for psittacosis

A

Chlamydophila psittaci

78
Q

Chlamydophila psittaci also known as

A

Ornithosis or parrot fever

79
Q

What are the three groups of rickettsia?

A
  • typhus group
  • spotted fever group
  • transituonal group
80
Q

Which species are the members of typhus group?

A
  • ricketssia prowazekii and ricketssia typhi
81
Q

Which species are the members of spotted fever group?

A
  • rickettsia rickettsii,
  • rickettsia conorii
  • rickettsia africae
82
Q

Which species are the members of transitional group?

A
  • rickettsia akari
  • rickettsia australis
  • rickettsia felis
83
Q

What is the vector in murine typhus?

A

Oriental rat flea or xenopsylla cheopis

84
Q

Causative agent of Epidemic louse-borne typhus

A

Rickettsia prowazekii

85
Q

Vector of louse borne typhus

A

Human louse (pediculus humanus), squirrel flea (orchopeas howardii), and squirrel louse (neohaematopinus sciuriopteri)

86
Q

Boutonneuse Fever also known as

A

Mediterranean spotted fever

87
Q

What is the vector of Rickettsialpox

A

Mouse mite (Liponyssoides
sanguineus)

88
Q

What is the vector of orienta tsutsugamushi

A

Chigger (Leptotrombidium deliensis)

89
Q

Causes Human granulocytotropic anaplasmosis

A

Anaplasma phagocytophilum

90
Q

Vector of human granulocytotrophic anaplasmosis

A

Western black-legged tick and deer tick

91
Q

exhibit a “twitching motility” in wet mounts

A

Bartonella bacilliformis and Bartonella benselae

92
Q

Trench Fever

A

B. quintana

93
Q

Cat Scratch Disease

A

B. benselae

94
Q

Infective Endocarditis

A

B. elizabethae

95
Q

Oroya Fever (Chronic Verruga
Peruana) and Febrile Acute Hemolytic
Anemia

A

B. bacilliformis

96
Q

Cat Scratch Disease (secondary
agent)

A

B. clarridgeiae

97
Q

Causative agent of Q (Query) Fever – a systemic
infection of the lungs

A

Coxiella burnetti

98
Q

Potential bioterrorism agent

A

Coxiella burnetti

99
Q

They multiply in the phagosome of the host leukocytes

A

Ehrlichia

100
Q

Presence of intravacuolar microcolony that
resembles “mulberries” or a morula

A

Ehrlichia

101
Q

detection of morulae during the febrile
stage of Ehrlichiosis

A

Giemsa stain

102
Q

used
for the cultivation of B. bacilliformis

A

Columbia blood agar with 5% defibrinated blood

103
Q

gold standard serologic test or reference method for Rickettsioses and Q fever

A

Indirect immunofluorescent antibody (IFA)
assay

104
Q

presumptive test for
Rickettsioses

A

Weil-Felix Reaction

105
Q

excellent
sensitivity for detecting antibodies to Rickettsia;
early diagnosis of RMSF

A

Microimmunofluorescent dot test

106
Q

It is the only test that is performed for the diagnosis of
rickettsial diseases

A

SEROLOGICAL TESTS