Miscellaneous articles 2018-2020 Flashcards
Plasma ammonia concentration after L-asparaginase therapy in 27 dogs with high-grade lymphoma or leukemia
jvecc 2018
Subclinical hyperammonemia in dogs w/ lymphoma or leukemia is after L-spar is common
How?
- Asparagine deaminated by asparaginase into ammonia + aspartic acid –> ammonia accumulate in plasma
- Asparaginase also has glutaminase activity to metabolize glutamine into glutamic acid + ammonia
Serum myoglobin, creatine kinase, and cell-free DNA in endurance sled dogs and sled dogs with clinical rhabdomyolysis
jvecc 2018
- cfDNA is not a useful biomarker compared to myoglobin and CK
- exertional rhabdomyolysis occurs early in endurance activities
- dogs w/ Cx had highest myoglobin and CK
Comparison of pentobarbital-phenytoin alone vs propofol prior to pentobarbital-phenytoin for euthanasia in 436 client-owned dogs.
Jessica M Bullock, Travis M Lanaux, and Justin W Shmalberg. jvecc 2019
Propofol reduced the incidence of muscle activity but no diff. in likelihood of adverse event with or without propofol
Assessment of hydromorphone and dexmedetomidine for emesis induction in cats.
Michael R Nystrom et al jvecc 2019
Dexmed 7 mcg/kg IM or hydromorphone 0.1 mg/kg SQ
Hydromorphone more successful than dexmed (75% vs 58%) AND less sedation and less decr in HR
Hydro caused mild elevation in temp
Immediate effect of transmucosal application of corn syrup or 50% dextrose solution on blood glucose concentrations in healthy dogs.
Rhonda L Holt, et al jvecc 2019
Sig. effect found 15 mins after application of 50% dextrose
supports use of parenteral dextrose in severely hypoglycemic pets
Retrospective evaluation of the severity of and prognosis associated with potassium abnormalities in dogs and cats presenting to an emergency room (January 2014-August 2015): 2441 cases.
Sabrina N Hoehne, et al jvecc 2019
Overall UNCOMMON:
- hypoK –> GI
- hyperK –> urinary tract
HypoK (dogs) and hyperK (Dogs and cats) had greater mortality than normoK
Mild hypoK and hyperK DOGS had higher mortality
Etiology and prognosis for dogs with abnormal blood glucose concentrations evaluated in an emergency room
hagley jvecc 2020
Hyperglycemia more common, associated w/ GI dz, trauma, cancer, resp dz – stress response?
Hypoglycemia (9%)- sepsis, GI dz, neoplasia
Dogs in shock/hyperlactatemia had higher BG than normal dogs
Mortality rate higher in those w/ dysglycemia.
Evaluation of the effects of hydroxyethyl starch (130/0.4) administration as a constant rate infusion on plasma colloid osmotic pressure in hypoalbuminemic dogs
Antonio Borrelli et al jvecc 2020
Gave HES in addition to crystalloids at 1 vs 2 mL/kg/hr to support COP
No diff in plasma COP b/w the two doses for 24h
Prospective evaluation of the influence of sampling method on bacterial culture results and antimicrobial selection in 52 dogs with infected wounds
Concannon et al jvecc 2020
diry swab (prior to prep), clean swab (after debridement + lavage), and bx samples
50/52 had +ve culture
Sampling technique didn’t affect population of wounds w/ anaerobic, g-ve, or MDR bacteria
-Overall # of g+ve recovery was lower for bx compared to clean or dry swab
Intestinal lymphoma in dogs: 84 cases (1997–2012)
Naoko Sogame javma 2018
MST 62 days
US: wall thickening with loss of layering and presence of ≥ 1 discrete mass
Anorexia and septic peritonitis were associated with poor prognosis.
Comparison of thoracic duct ligation plus subphrenic pericardiectomy with or without cisterna chyli ablation for treatment of idiopathic chylothorax in cats
Stephen L. Stockdale javma 2018
Adding CCA to TDL + SPC prolonged surgery time without improvement in outcome
Evaluation of the diagnostic utility of cytologic examination of renal fine-needle aspirates from dogs and the use of ultrasonographic features to inform cytologic diagnosis
Camille A. McAloney, javma 2018
Renal FNA specimens were adequate for interpretation at rates comparable with those reported for other organs and were considered clinically useful for diagnosis of neoplasia.
Sensitivity for detecting LSA was 100%
Clinical findings and outcomes for dogs with uveodermatologic syndrome
Mitzi K. Zarfoss, javma 2018
UDS commonly resulted in glaucoma, vision loss, or both in affected dogs.
No evaluated factor was associated with visual prognosis
UDS =immune-mediated damage to melanin-laden tissues
-bilateral panuveitis with pigment dispersion within the anterior chamber of the eye, retinal detachment, response to immunosuppressive treatment, and breed (Akita»_space;> Siberian Huskies and Samoyeds)
Effect of refrigeration of clinical canine urine samples on quantitative bacterial culture
Mark J. Acierno javma 2018
Canine urine samples collected for bacterial culture should be immediately submitted for testing.
CFU counts for refrigerated and immediately processed samples were statistically similar
Sample refrigeration in enrichment broth resulted in imperfect sensitivity for UTI detection and is not recommended.
Acute masticatory muscle compartmental syndrome in a dog
Megan T. Cray javma 2018
Acute compartmental syndrome should be considered as a differential diagnosis for dogs with a sudden onset of severe skeletal muscle swelling, signs of pain, and dysfunction.
Findings for this dog with acute compartmental syndrome isolated to the masticatory muscles suggested that emergent fasciotomy followed by medical management may be an effective tx
Development and evaluation of a formula to correct blood glucose concentration measurements in hemodiluted and hemoconcentrated feline blood samples tested by use of a veterinary point-of-care glucometer
Lane javma 2019
POCglucose and labglucose didn’t correlate well in anemic or hemoconcentrated samples
Corrected POCgluc = POCgluc + ([1.17 × PCV] – 50.2).
Analysis of outcomes following treatment of craniodorsal hip luxation with closed reduction and Ehmer sling application in dogs
Schlag JAVMA 2019
Ehmer slings from craniodorsal hip lux had low success rate (56%) and high complication rate (18%)
-superficial pyoderma, pressure necrosis wound, urine scale, edema @ distal part of affected limb
Those who had traumatic hip lux and w/ polytrauma had higher reluxation risk
Comparison of complications and outcome following unilateral, staged bilateral, and single-stage bilateral ventral bulla osteotomy in cats
JAVMa 2019
Staged bilateral VBO is recommended over single-staged bilateral VBO in middle ear dz
-single-staged more likely to have resp complications + sx-related death
Horners, head tilt and facial nerve paralysis more likely to persist in those who had signs pre-op.
