Miscarriage Flashcards
What is a miscarriage?
The loss of a pregnancy <24weeks gestation
What is an early miscarriage?
1st trimester (<12 weeks)
What is a late miscarriage?
2nd trimester (13-24 weeks)
What percentage of pregnancies result in miscarriage?
20-25%
List the risk factors for miscarriage
Maternal age >30-35 (increase in chromosomal abnormalities) Previous miscarriage Obesity Chromosomal abnormalities Smoking Uterine anomalies (fibroids and adhesions) Previous uterine surgery Anti-phospholipid syndrome Coagulopathies
List the clinical features of misccariage
Vaginal bleeding - clots/products of conception
If heavy bleeding then haemodynamic instability - pallor, SOB, dizziness
Suprapubic cramping pain
List the signs of miscarriage on examination
Haemodynamic instability - pallor, tachycardia, tachypnoea, hypotension
Abdominal examination - Abdomen may be distended with localised areas of tenderness
Speculum examination - assess the diameter of the cervical os and observe for any products of conception in cervical canal or local areas of bleeding
Bimanual examination - assess any uterine tenderness and any adnexal masses or collections
List the differentials for miscarriage
Ectopic pregnancy
Hydatiform mole
Cervical/uterine malignancy
What is the main diagnostic investigation of miscarriage?
Transvaginal ultrasound
What can gestation be estimated by?
Foetal crown rump length
What is required if foetal crown rump length is <7mm and no foetal heart can be identified?
Repeat scan in 7 days
If a foetal pole is not visible but intrauterine pregnancy is confirmed with gestational sac and yolk sac, what does management depend on?
The mean sac diameter
>25mm - failed pregnancy
<25mm - repeat scan 1-14days later
What other investigations can be done for someone with suspected miscarriage?
Serum b-HCG - rule out ectopic
FBC
Blood group and rhesus status
Triple swabs and CRP if pyrexial
What is given regardless of treatment type to a woman experiencing a miscarriage?
Anti-D immunoglobulin if Rh-ve mother and >12weeks gestation or managed surgically regardless of gestation
What are the 3 definitive management options for miscarriage?
Conservative (expectant)
Medical
Surgical