Misc Bacteria

Question 1

Obligate intracellular bacteria (cannot make ATP), has 2 forms, cell wall lacks muramic acid, cultured in tissue cultures, causes 3 distinct diseases, infects nonciliated columnar or cuboidal epithelial cells of mucosal surfaces that causes a granulomatous response and damage

Answer 1

Chlamydia trachomatis

Question 2

Most common bacterial STD in US, causes urethritis, cervicitis, PID, can causes inclusion conjunctivitis or pneumonia in neonates (pneumonia characterized by staccato cough)

Answer 2

Chlamydia trachomatis, serotypes D-K

Question 3

Infectious form of chlamydia? Replicating form?

Answer 3

Infectious = elementary body

Replicating = reticulate body

Question 4

STD causing swollen lymph nodes that may lead to elephantiasis, ulcers, or fistula formation

Answer 4

Lymphogranuloma venereum caused by Chlamydia trachomatis, serotypes L1, 2, 3

Question 5

Leading cause of preventable infectious blindness, causes follicular conjunctivitis that leads to inturned eyelashes and corneal scarring

Answer 5

Trachoma, causesd by Chlamydia trachomatis serotypes A-C

Question 6

Cause of atypical pneumonia associated with atherosclerosis, diagnose with serology

Answer 6

Chlamydophila pneumoniae

Question 7

Cause of atypical pneumonia associated with hepatitis, no glycogen seen in inclusion bodies, associated with exposure to parrots or turkeys, diagnose with serology

Answer 7

Chlamydophila psittaci

Question 8

Aerobic bacilli, technically G- but too small to stain, obligate intracellular, transmitted by Dermacentor tick, invades endothelial cells to cause vasculitis, highest incidence in North Carolina

Answer 8

Rickettsia rickettsii

Question 9

Symptoms of Rocky Mountain Spotted Fever?

Answer 9

headache, fever, myalgias, vomiting, confusion, maculopapular -> petechial rash that starts on ankles and progresses to trunk and face, ankle and wrist swelling

Question 10

G- obligate intracellular bacilli, found in same geographic area and transmitted by same tick as Borrelia, presents similarly to Rocky Mountain Spotted Fever but without the rash, causes a morulae (mulberry like structure inside infected cell)

Answer 10

Ehrlichia chaffeensis/phagocytophila

Question 11

Smallest extracellular bacteria, no cell wall, requires cholesterol for culture, grows mulberry colonies on Eaton’s media, positive cold agglutinins, causes an atypical pneumonia

Answer 11

Mycoplasma pneumoniae

Question 12

Virulence factors of M. pneumoniae?

Answer 12

P1 protein - attachment

Inhibition of ciliary action

Produces H2O2, superoxide radicals, and cytolytic enzymes that damage the respiratory epithelium

Superantigen elicits IL1, IL6, TNF-a

Question 13

Adult patient with urethritis, prostatitis, renal calculi, urease +, non gram staining, member of Mycoplasmataceae

Answer 13

Ureaplasma urealyticum