MINOR BLOOD GROUP SYSTEM

Question 1

ISBT 010

Answer 1

Diego System

Question 2

Diego gene location

Answer 2

Chromosome 17q

Question 3

DIEGO
Antigens are located on what protein?

Answer 3

Band3 protein (anion exchanger /AE-1)

Question 4

Diego antigen that served as a useful tool in anthropologic studies of Mongolian ancestry.

Answer 4

Di^a

Question 5

Diego Antibodies
Anti Wra:________
Anti-ELO: ________

Answer 5

Anti-Wra: IgG at most, some at IgM, have cause severe HTR and HDN

Anti-ELO: severe HDN

Question 6

ISBT 011

Answer 6

Cartwright system

Question 7

Cartwright gene location

Answer 7

Chromosome 7q

Question 8

Cartwright high prevalence antigen

Answer 8

Yta

Question 9

Cartwright low prevalence antigen

Answer 9

Ytb

Question 10

Yt antigens are located on ____________ which is an enzyme involved in neurotransmission.

Answer 10

Erythrocyte Acetylcholinesterase

Question 11

3 phenotypes observed in Cartwright

Answer 11

Yt (a+b-) (91.9 %)
Yt (a+b+) (7.8%)
Yt (a-b+) (0.3%)

Question 12

ISBT 012

Answer 12

Xg system

Question 13

Xg gene location

Answer 13

Short arm of X chromosome

Question 14

2 antigens of Xg system

Answer 14

Xga
CD99 (aka 12E7 and MIC2)

Question 15

Xg system: Have high expression of CD99 on their RBCs

Answer 15

Xg (a+)

Question 16

Xg system: Antigen that has low expression of CD99 in females

Answer 16

Xg(a-)

Question 17

ISBT 013

Answer 17

Scianna system

Question 18

Scianna gene location

Answer 18

Chromosome 1p

Question 19

ISBT 014

Answer 19

Dombrock system

Question 20

Dombrock gene location

Answer 20

Chromosome 12p

Question 21

Dombrock highly immunogenic antigen

Answer 21

Gya

Question 22

ISBT 15

Answer 22

Colton system

Question 23

Colton gene location

Answer 23

Chromosome 7p

Question 24

Colton antigens that are expressed in the tissues of the proximal and descending tubules and thee collecting ducts of kidney and are believed to account 80 % of the reabsorption of water.

Answer 24

AQP1 and CO antigens

Question 25

ISBT 016

Answer 25

Landsteiner- Weiner system

Question 26

Landsteiner-Weiner gene location

Answer 26

Chromosome 19p

Question 27

LW antigens are carried on___.

Answer 27

ICAM-4

Question 28

Landsteiner-Weiner antigen that react strongly with D+ RBCs

Answer 28

Anti-LW

Question 29

ISBT 017

Answer 29

Chido-Rodgers system

Question 30

Chido-Rodgers gene location

Answer 30

Chromosome 6p

Question 31

Chido-Rodgers C4A carries what system?

Answer 31

Rodgers

Question 32

Chido-Rodgers C4b carries what system?

Answer 32

Chido

Question 33

They are generally 1gG2 and IgG4 subclasses and are considered clinically insignificant

Answer 33

Chido-Rodgers antibodies

Question 34

ISBT 020

Answer 34

Gerbich System

Question 35

Gerbich gene location

Answer 35

Chromosome 2q

Question 36

ISBT 021
What is it’s gene location?

Answer 36

Cromer system
Chromosome 1q

Question 37

ISBT 022
Gene location?

Answer 37

Knops system
Chromosome 1q

Question 38

ISBT 023
Gene location?

Answer 38

Indian system
Chromosome 11q

Question 39

Carried by hematopoietic isoform of the CD 44 marker

Answer 39

IN (indian) antigens

Question 40

ISBT 024
Gene location?

Answer 40

Ok system
Chromosome 19p

Question 41

ISBT 026
Gene location?

Answer 41

John Milton Hagen (JMH) system
Chromosome 15

Question 42

Phenotypes predominantly found in BLACKS

Answer 42

At(a-)
Cr(a-)
Jo(a-)