ABO HDN Flashcards
1
Q
Most common HDN
A
ABO HDN
2
Q
Group O mother’s + Group A/B fetus = HDN (mild)
Why mild?
A
- presence of A or aB substance in fetal tissues and secretions reduces the amount of ABO antibody available to destroy red cells.
- poor development and reduced number of ABO antibody
- explains why DAT is only weak positive in most cases of ABO HDN
3
Q
Hyperbilirubinemia and jaundice occurs after how many hours after birth?
A
12-48 hours after birth
4
Q
Treatment for ABO HDN
A
PHOTOTHERAPY or IV Ig
5
Q
When is ABO HDN screening best done?
A
Post- natal
6
Q
Most important diagnostic test of ABO HDN
A
DAT
7
Q
Specimen used for DAT
A
Cord blood or neonatal RBCs
8
Q
Reveals when the ABO antibodies is negative in DAT
A
Eluate of the cord RBCs
9
Q
Hgb in mild ABO HDN
A
> 13g/dL
10
Q
Blood smear morphology
A
Spherocytosis
