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NAPLEX > Migraine > Flashcards

Migraine Flashcards

0
Q

List common migraine triggers

A

Hormonal changes in women

Foods

Stress

Sensory stimuli

Changes in wake-sleep pattern

Changes in the environment

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1
Q

What’s Triptans?

A

5HT1 Serotonin-receptor agonists that cause vasodilation of cranial blood vessels

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2
Q

What’s used for acute tx?

A

Triptans

NSAIDs or Excedrin Migraine

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3
Q

List triptans used in migraine

A

Naratriptan (Amerge)

Almotriptan (Axert)

Frovatriptan (Frova)

Sumatriptan (Imitrex, Alsuma)

Eletriptan (Relpax)

Rizatriptan (Maxalt, Maxalt-MLT)

Zolmitriptan (Zomig, Zomig-ZMT disint tabs)

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4
Q

Brand name of Sumatriptan? (Needleless sumatriptan injection)

A

Imitrex

Alsuma

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5
Q

Brand name of Sumatriptan? (SC injection)

A

Imitrex STATdose SC dose

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6
Q

Brand name of Sumatriptan? (Nasal spray)

A

Imitrex nasal spray

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7
Q

Brand name of Rizatriptan?

A

Maxalt

Maxalt-MLT

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8
Q

Brand name of Eletriptan?

A

Relpax

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9
Q

Ses of Triptans?

A

Triptan sensations, includes pressure in the chest or heaviness or pressure in the neck region and usually dissipate after admin

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10
Q

Which triptans has a nasal and SC inj formulation?

A

Sumatriptan

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11
Q

Long-acting (but slower onset) triptans?

A

Frovatriptan (Frova)

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12
Q

Shorter half-life (duration) but quick onset triptans?

A

Almotriptan (Axert)

Eletriptan (Replax)

Rizatriptan (Maxalt)

Sumatriptan (Imitrex, Alsuma)

Zolmitriptan

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13
Q

Which triptans are CI with MAO-I use?

A

Imitrex (Sumatriptan)

Maxalt (Rizatriptan)

Zomig (Zolmitriptan)

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14
Q

When should migraine prophylaxis be considered?

A

Migraine tx > 2 x a wk

Or

Migraine decreases quality of life

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15
Q

What’s 1st line agents for migraine prophylaxis?

A

Beta-blockers e.g.
Propranolol (Inderal)
Timolol (Blocadren)
Metoprolol (Lopressor, Toprol XL)

Valproate
Topiramate (Topamax)

16
Q

What’s 2nd line agents for migraine prophylaxis?

A

Other beta-blockers

ACE-I

Antidepressant

Natural pdts

OCPs (for premenstrual migraine)

Botulinum toxin type A (chronic migraine only…last >= 15 days/month)

17
Q

Ses of valproate/Divalproex?

A

Liver toxicity

Pancreatitis

Weight gain

Teratogenicity

Thrombocytopenia

18
Q

SEs of Topiramte?

A

Weight loss

19
Q

Whens Botulinum toxin type A used in migraine?

A

For chronic migraine only…last >= 15 days/month

20
Q

Do u prime Zomig and Imitrex spray before use?

A

NO!!!!!!!!

21
Q

Where do u admin Imitrex-STAT dose?

A

SC, upper outside arm

22
Q

Which med is approved to treat pre-menstrual migraine + aura in women?

A

Nor-QD

Nora-Be

Camila

23
Q

What does Fiorinal contain? Class in CS?

A

Aspirin + Butalbital + Caffeine

C-III

24
Q

How often do u repeat the dose of Sumatriptan? PO, Nasal spray, SC injection

A

PO & Nasal spray - can repeat after 2 hrs

SC - after 1 hr

NAPLEX (73 decks)

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