Common Skin Conditions - Skin Fungal Inf

Question 0

What’s Jock itch (Tinea cruris)

Answer 0

Affects the genitals, inner thighs and buttocks

Question 1

What’s athletes foot (tinea pedis)?

Answer 1

Fungal infection caused commonly by TRICHOPHYTON RUBRUM

Question 2

What’s ringworm (tinea corporis)?

Answer 2

Not a worm, but skin infection

Looks like circular, red, flat sores

Question 3

What’s Tinea capitis?

Answer 3

Ringworm on the scalp

Question 4

In what grp of people is cutaneous (skin) candida infection most common?

Answer 4

Obese people bcuz they have more skin with folds

Question 5

List drugs used for skin fungal tx?

Answer 5

Terbinafine and butenafine (highly effective)

Clotrimazole

Question 6

What’s the brand name of Terbinafine? How does it come?

Answer 6

Lamisil AT cream and soln

Question 7

List non-pharmacologic ways to treat fungal skin inf?

Answer 7

Reduce moisture to infected area

If foot ing, don’t walk barefoot (to avoid spreading it)

Wear scandals in public showers

Question 8

What’s important for diagnosis of Onycomycosis (Tinea Unguium)?

Answer 8

20% potassium hydroxide (KOH) smear is essential for diagnosis as other conditions are similar

Question 9

List agents used for Onycomycosis (Tinea Unguium)

Answer 9

Itraconazole (Sporanox)

Terbinafine (Lamisil, Terbinex)

Ciclopirox (Penlac, Loprox)

Question 10

What’s the difference btw Lamisil and Lamisil AT?

Answer 10

Lamisil is oral Terbinafine

Lamisil AT is topical Terbinafine (used for fungal skin inf)

Question 11

What’s the brand name of Itraconazole?

Answer 11

Sporanox

Question 12

What’s the black box warning associated with Itraconazole (Sporanox)?

Answer 12

Avoid use in HF

Req gastric acid for absorption

Can’t use strong acid suppressing agents concurrently

Question 13

SE of systemic terbinafine (Lamisil, Terbinex)?

Answer 13

Headache (primarily)

Rash

Nausea

Risk of hepatotoxicity

Question 14

What should be monitored using systemic antifungals? (Itraconazole - Sporanox; Terbinafine - Lamisil, Terbinex; Ciclopirix - Penlac, Loprox)?

Answer 14

Liver enzymes/ sx of liver toxicity

Question 15

What’s the sx of vaginal fungal candida (yeast) infection?

Answer 15

Itching with soreness and pain (burning) during urination or sex

Question 16

What natural pdt is considered possibly effective in vaginal fungal candida (yeast) inf?

Answer 16

Lactobacillus or yoghurt with active cultures

Question 17

What’s used in mild-moderate, infrequent inf?

Answer 17

OTC, topical agents

Butoconazole
Clotrimazole 
Miconazole (Monistat)
Terconazole 
Tioconazole (Vagistat-1)

Question 18

What’s the duration of tx in mild-moderate, infrequent vaginal yeast inf?

Answer 18

1 or 3 day tx

Question 19

What’s used in complicated vaginal yeast infections and in pregnancy?

Answer 19

Fluconazole (Diflucan)

7-10 days tx

Question 20

What should be avoided with use of OTC antifungals (for vagina yeast inf)?

Answer 20

Avoid sexual intercourse (creams and suppositories are oil-based and
can weaker latex condoms and diaphragm)

Don’t use tampons during tx

Question 21

What’s essential in Eczema (Atopic Dermatitis) tx?

Answer 21

Hydration is essential

Use moisturizers (petrolatum, lanolin, pdts such as Aquaphor, Eucerin, Keri or store brands)

Question 22

List agents used in Eczema (Atopic Dermatitis)

Answer 22

Topical corticosteroids

Antihistamines (for itching)

Immune-suppressant calcineurin inhibitors (if topical steroids + hydration are not adequate)

Question 23

Whats the 1st line of tx for Eczema (Atopic Dermatitis)?

Answer 23

Topical steroids

Question 24

What’s used as last-line in Eczema (Atopic Dermatitis)?

Answer 24

Tacrolimus (Protopic)

Pimecrolimus (Elidel)

Question 25

How do u use Tacrolimus (Protopic) and Pimecrolimus (Elidel)?

Answer 25

Apply thin layer only to affected skin areas, twice a day

Use smallest amt needed to control sx

Wash hands after application

Question 26

Why is Lindane (Kwell) no longer used for lice tx?

Answer 26

Bcuz of neurotoxicity

Question 27

List agents used in lice

Answer 27

Pyrethrins (permethrin) OTC drug of choice

Malathion lotion 0.5% (Ovide)

Benzyl alcohol lotion (Ulesfia 5% lotion)

Lindane shampoo 1%

Question 28

Which lice agent kills live lice but not nits?

Answer 28

Benzyl alcohol lotion (Ulesfia 5% lotion)

Question 29

What’s the OTC drug of choice for lice?

Answer 29

Permethrin (Pyrethrins)

Question 30

What can be done in addition to OTC lice tx?

Answer 30

Remove live lice and nit (use 1-inch segments and lice comb)

Without removing live lice and nit, OTC pdt won’t work

Question 31

When is tx of genital warts not req?

Answer 31

When there’s no sx

Question 32

What agent is used in genital warts?

Answer 32

Imiquimod cream

Question 33

How to use imiquimod cream?

Answer 33

Apply to entire tx area b4 bedtime and rub in unit cream is no longer visible

Use only 1 packet per application

Wash off after 8 hrs

Apply 3x/wk until clearance or 16 wks duration

Question 34

What’s the primary tx for skin irritation?

Answer 34

Topical steroids

Question 35

What strength of topical steroids is OTC?

Answer 35

Hydrocortisone (HC) OTC, 0.5%, 1%

All other topical strength are rx

Question 36

Rank different dosage forms from highest potency to weakest potency? (Creams, lotions, ointment, sprays, gel)

Answer 36

Ointment > creams > lotions > solns > gels > spray

Question 37

What’s used to represent pea-sized amt?

Answer 37

Finger-tip unit