MIDTERMS CA Flashcards
part of the autonomic nervous system located near the thoracic and lumbar regions in the spinal cord.
SYMPATHETIC SYSTEM
It is located in between the spinal cord and the medulla. It primarily stimulates the body’s “rest and digest” and “feed and breed” responses.
PARASYMPATHETIC SYSTEM
Autoimmune destruction of beta cells leading to absolute insulin deficiency
Requires insulin therapy for management
Commonly diagnosed in childhood or adolescence
Type 1 Diabetes Mellitus
Insulin resistance and progressive loss of beta-cell insulin secretion
Type 2 Diabetes Mellitus
recommended as the initial pharmacological approach for patients with type 2 diabetes, as it reduces HbA1c levels, decreases cardiovascular disease risk independent of glycaemic control, may assist with weight loss and has a low risk of hypoglycaemia.
Metformin
make insulin, a hormone that controls the level of glucose in the blood
Beta cells
releases glucagon, which elevates blood glucose
Alpha cells
Layered with plaque, the artery walls become narrow and rigid. Narrower, less distensible arteries restrict the flow of blood to the heart.
atherosclerosis.
FIRST LINE TREATMENT
Atherosclerosis
Calcium Channel Blockers (CCB)
Angiotensin Converting Enzyme inhibitors (ACE inhibitors or ACE-I) and Angiotensin Receptor Blockers (ARBs)
Diuretics
target L-type calcium channels and binds to them. These L-type calcium channels are located on the smooth muscle
Calcium-channel blockers
both work by lowering the effects of angiotensin-2 (pronounced: an-jee-oh-TEN-sin 2) in the body. Angiotensin-2 is also known as AT2.
ACE inhibitors and ARBs
medicines that help reduce fluid buildup in the body. They are sometimes called water pills.
Diuretics
caused by reduced blood flow to the heart muscle. Blood carries oxygen, which the heart muscle needs to survive. When the heart muscle isn’t getting enough oxygen, it causes a condition called ischemia.
ANGINA
FIRST LINE TREATMENT
Angina
Beta-blockers
Calcium channel blockers or long-acting nitrates
may be appropriate for those who do not tolerate or who have contraindications to beta-blockers.
Calcium channel blockers or long-acting nitrates