Midterm 2 (Development of the brain) Flashcards
what two things does brain development depend on?
maturation and learning
when does the human central nervous system begin to form?
when the embryo is approx. two weeks old
first step of human CNS formation
the dorsal surface thickens, forming a neural tube surrounding a fluid filled cavity
second step of human CNS formation
the forward end enlarges and differentiates into the hindbrain, midbrain and forebrain
third step in human CNS formation
the rest of the neural tube becomes the spinal cord
how much does a brain weigh at birth, by the first year, and adulthood (grams)
birth- 350g
first year- 1000g
adult- 1200-1400g
list the five steps of development of neurons
proliferation, migration, differentiation, myelination, and synaptogenesis
define “proliferation” in the context of neuron development
the production of new cells/ neurons in the brain primarily occurring early in life
define “migration” in the context of neuron development
the movement of the newly formed neurons and glia to their eventual locations
define “differentiation” in context of neuron development
the forming of the axon and dendrites that gives the neuron its distinctive shape
define “myelination” in the context of neuron development
the process by which glia produce the fatty sheath that covers the axons of some neurons
define “synaptogenesis” in the context of neuron development
(the final stage of neural development) the formation of the synapses between neurons
what are Neurotropins?
chemicals that promote the survival and activity of neurons
describe the dendrites of children born with fetal alcohol syndrome
short with few branches
what does exposure to alcohol in a fetus brain suppress? what does it enhance?
suppresses glutamate and enhances the release of GABA