Midterm 2 Flashcards
Homologous chromosomes
The two chromosomes make up math pair in diploid cell. Homologous chromosomes of the same length, centromere position, and staining pattern, possess genes for the same characters at corresponding loci. One homologous chromosome is inherited from the organism’s father, the other from the mother.
They are at the locus, usually can be;
Different Alleles
- Dominant B
- Recessive b
Homozygous
An organism that has two identical alleles for a gene is said to be homozygous for that gene.
Heterozygous
An organism that has two different alleles for a gene is said to be heterozygous for that gene.
Genotypes
Genetic make up (eg. PP,Pp,pp)
Who or what was Mandel?
Was the first to link patterns of inheritance to the combination of discrete units (later known as genes)
Why does genes exist and has to be with alleles and genotypes?
Genes exist as pairs and type of allele pairing having as a result the genotype.
Inheritance is involve in what?
Involves in the segregation and recombination of alleles.
Phenotype
Observable traits (eg. purple or white flowers)
How is a heritable feature called?
It’s called Character
How is it called each variant of a character?
It’s called Trait.
When does segregation occurs?
Occurs during Meiosis
When does recombination occurs?
Occurs during Fertilization
What does Cell Division results?
Results in daughter cells identical to the parent.
division = reproduction
In single celled organisms
When does division = growth / replacement?
In multicellular organisms
What should happen before division?
the chromosome/s must be replicated
Main distinctions between Binary fission and Mitosis
Binary fission primarily occurs in Prokaryotes (bacteria), while on Mitosis occurs in Eukaryotes (plant and animal cells).
Mitotic Spindle Structure
Ensures that all chromosomes are correctly divided.
During Interphase
The cell grows and makes a copy of its DNA.
During Mitotic Phase
The cell separates its DNA into two sets and divides its cytoplasm, forming two new cells.
During Mitosis
A Eukaryotic cell nucleus splits in two, followed by division of the parent cell into two daughter cells.
Stages of the cell cycle
G1 - Growth (increase in size)
S - DNA Synthesis (copies its DNA)
G2 - Growth and preparation (prepares to divide)
M - Mitosis (and divides)
Diploidy
The presence of two complete sets of chromosomes in an organism’s cells, with each parent contributing a chromosome to each pair.
23 haploid
Chromosomes are known as the sex chromosomes. Male and female have 23 chromosomes.
46 diploid
Is the total chromosomes, half come from the mother, the other half from the father.
44+2
humans would deviate from the current state of human DNA which contains 44 = autosomes, and 2 = sex chromosomes.
What happens during cancer?
the cell cycle is dysregulated, due to mutations.
What is a Generic disease?
occur when a mutation (a harmful change to a gene, also known as a pathogenic variant) affects your genes or when you have the wrong amount of genetic material. (E.g Down Syndrome).
What is a Inherited disease?
Conditions in which the genetic changes are almost exclusively responsible for causing the condition. (E.g. spinal muscular atrophy).