Midterm 1 Flashcards
Visual pathway order
retina, ON. chiasm, tract, lgn, radiations, striate cortex
synapse 1
PR cell
- photon strikes photopigment
- photopigment splits- chemical rxn produce message
synapse 2
bipolar cell
between PR and Gang
synapse 3
ganglion cell
axons (optic nerve) –> optic chiasm –> optic tract
synapse 4
LGN neuron
axon –> optic radiations
which part of the ON is the longest?
intraorbital
what part of the sphenoid does the ON go through?
lesser wing
list the parts of the ON from shortest to longer
intraocular < intracanalicular < intracranial < intraorbitll
how many fibers does the ON have
1-2.2 million
what is the horizontal diameter of ONH
1.5 mm (1500um)
what is the prelaminar part of the intraocular nerve
fascicles: sheats of astrocytes bundle ~1000 fibers per fascicle
what is the laminar part of the intraocular nerve
within the lamina cribosa
pathway of ganglion cells
ganglion cells from retina to LGN then become optic radiations
what is the lamina cribosa
network of sclera fibers where the ON exits the eye
- if IOP goes up –> damage to the perforated nerve fibers that are in the sclera
intraorbital portion of the ON diameter
3mm
intraorbital portion of the ON postlaminar
Fascicles acquire a connective tissue sheath and become myelinated by oligodendrocytes
-surrounded by EOMs
what is longer: globe or intraorbital
intraorbital is loner than the apex-apex measurement of the globe
what is between the fascicle in the post laminar part of the ONH
glial tissue is between the fascicle
why is the infraorbital portion of ON so long?
need wiggle room to look around
where is myelination only located?
post laminar
increases CSF affect on ON
push on it and it swells
which layer of the meningeal sheath has a lot of BV
PIa- helps profuse parts of the ON
what does glial tissue in the ON do
separates the nerve form the retina, choroid, sclera
Intermediary tissue (of Kuhnt)
Glial tissue separating the retina
Border tissue (of Jacoby)
Glial tissue separating the choroid
Marginal tissue (of Elschnig)
Connective tissue continuous with the sclera
what is the ON inferior to?
olfactory tract and anterior cerebral artery
what is the ON superior and medial to?
ICA
what is the ON lateral to?
sphenoid body
what is the sheath of the optic nerve attached to
sheath of EOM
what two muscles does the optic nerve attach too?
MR and SR
what supplies the prelaminar and laminar portions of the ON
prepapillary choroidal network, unfenestrated
what supplies the postlaminar portion of the ON
Ophthalmic artery
Central retinal artery
Pial vessels
what supplies the intracranial
Ophthalmic artery
Anterior cerebral artery
Anterior communicating artery
Internal carotid artery
what does the circle of willis surrond
chiasm
what is the chiasm posterior and interior to
anterior cerebral and communicating arteries
what is the chiasm medial to
internal carotid arteries
what is the chiasm inferior to
3rd v
what is the chiasm superior to
pituitary gland
what supplies blood to the chiasm from the superior network
Anterior communicating artery
Anterior cerebral artery
what supplies blood to the chiasm from the inferior network
Posterior communicating artery
Posterior cerebral artery
Internal carotid artery
what is a flattened cylindrical band of ganglion fibers from the chiasm to LGN
optic tract
where to 90% of the fibers from the optic tract go
LGN
where do 10% of the fibers from the optic tract go
Pretectal area
Superior colliculus
Hypothalamus
what is lateral to the optic tract
cerebral peduncle
what is parallel to the optic tract
posterior cerebral artery
what is inferior to the optic tract
globus pallidus
what supplies blood to the optic tract
Anterior choroidal
Middle cerebral
where is the LGN located
dorsolateral portion of the pulvinar thalamus
where do retinal axons terminate
LGN
magnocellular layer
layer 1-2 large motion/ low spatial frequency upper/dorsal stream where/how 4ca
parvocellular layer
layers 3-6 small high contrast, detail, high spatial frequency ventral stream what 4cb
koniocellular layers
dispersed - dust like- small- color vision and high frequency
what is the function of the LGN
visual processing
- Ensures the most important information is sent to the visual cortex
- Has a pathway to the visual cortex and other cortical areas
- Has a pathway from the visual cortex
what is medial to the lgn
internal capsule and inferior horn of the lateral ventricle
what is lateral to the lgn
medial geniculate nucleus
what supplies the LGN
Anterior choroidal artery
Posterior choroidal artery
what is another name for optic radiations
Geniculocalcarine Tract
what part of the brain do the optic radiations pass through
parietal and temporal lobe
what is lateral to the optic radiations
inferior horn of the lateral ventricle
what supplies the anterior radiations
anterior choroidal artery
what supplies the middle radiations
deep optic branch of the middle cerebral artery
what supplies the posterior radiations
calcarine branch of the posterior cerebral artery
what are other names for the primary visual cortex
striate cortex
Brodmann Area 17
V1
where is the primary visual cortex located
- Medial portion of the occipital lobe
- Line of Gennari runs near the calcarine fissure
what separates the cuneus gyrus and lingual gyrus
- Calcarine fissure
- Intersects the parietooccipital sulcus
function of the primary visual cortex
Process visual information
Integration of binocular information
visual cortex vertical organization
- Ocular dominance columns
- Columns for stimulus orientation
- Responds to the direction of light
what eye does 146 to go to
opposite
what eye does 235 go to
same side
blood supply to the primary visual cortex
Calcarine branch of the posterior cerebral artery
Visual association areas other names
Brodmann areas 18, 19 now referred to as V2, V3, V4, V5
Visual association areas functions
Functions as storage for visual patterns and recall
striate connections to the superior collculus
fixation and saccades
striate connections to the hypothalamus
Circadian rhythm
striate connections to frontal eye fields
Voluntary and reflexive binocular eye movements
striate connections to
nucleus of the optic tract
Optokinetic nystagmus (OKN)
retinal nerve fiber layer
-Ganglion cell axons
- Papillomacular bundle
- Horizontal raphe
where do macular fibers move towards
the center
where do the superior temporal fibers exit to
medial optic tract
where do the superior nasal fibers cross
cross to contralateral, medial optic tract
-posterior knees of wilbrand
inferior temporal fibers exit to the
lateral optic tract
where do inferior nasal fibers cross
contralateral lateral optic tract
-anterior knees of wilbrand
nasal fibers cross to
contralateral eye
what two fibers go into eye
ipsilateral temporal fibers and contralateral nasal fibers
what fibers are seen in the optic tract
Superior peripheral fibers
Inferior peripheral fibers
Macular fibers are in the middle
what fibers are seen in the LGN
Superior peripheral fibers
Inferior peripheral fibers
Macular fibers
optic radiation superior fibers
Parietal lobe
optic radiations Inferior fibers
Temporal lobe
- meyers loop
Visual cortex Superior fibers
cuneus gyrus
Visual cortex Inferior fibers
lingual gyrus
where are the macular fibers in the visual cortex
run posterior
retinal defects: temporal field is imaged in the
nasal retina
retinal defects: superior field is imaged in the
inferior retina
Right side of visual field imaged in ____ retina of the right eye and ____ retina in the left eye
- nasal
2. temporal
characteristics of retinal defects
unilateral, irregular shaped, can cross the horizontal and vertical midlines
visual field of retinal nerve fiber layer
- Group of ganglion cells
- Arcuate scotoma or nasal step
- Horizontal midline typically respected
visual field of optic nerive
Central or centrocecal defect
With compression, macular fibers are often affected first
(+)APD, afferent pupillary defect - defect in ganglion cell fibers
visual field of chiasm
Optic Chiasm
First place where a single lesion will affect both eyes
Nasal fibers cross the midline
VF of pituitary gland adenoma
Bitemporal hemianopia
what is the pituitary gland inferior to
optic chiasm
Involves both lateral sides of the chiasm
Binasal hemianopia
Anterior Junction Syndrome
- Compression of the optic nerve at its junction with the chiasm
- Central defect in ipsilateral eye
- “pie in the sky” in the contralateral eye
Post-chiasmal lesions
Damage affects the contralateral field
- Homonymous hemianopia
- Incongruent - closer to chiasm
- Congruent - further from the chiasm
- Vertical midline respected
Optic tract: Right visual field carried in __ optic tract
left
Optic tract: Left visual field carried in __optic tract
right
when are pupils affected in the optic tract
if lesion is in the anterior 2/3 of the tract
what type of vfl does lgn have
Homonymous loss
what type of vfl do optic radiations have
Likely a quadranopsia
Visual cortex
visual field
- Congruent homonymous hemianopia
- Visual acuity usually not affected
- Macular sparing vs macular splitting
Temporal crescent
Portion of the peripheral field without a counterpart in the nasal field of the other eye
-Located very _anterior__ in the visual cortex
visual field for prechiasmal
monocular