midterm 1 Flashcards

1
Q

which of the following is mainly an inflammatory reaction
1. necrosis
2. apoptosis
3. autophagy
4. programmed cell death

A

1

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2
Q

which of the following sees DNA laddering
1. necrosis
2. apoptosis
3. autophagy
4. programmed cell death

A

2

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3
Q

________ sees late membrane damage, while ______ is early damage

A

apoptosis
necrosis

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4
Q

where is the cell more likely to swell
1. necrosis
2. apoptosis
3. autophagy
4. programmed cell death

A

1

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5
Q

intrinsic apoptosis depends on

A

the mitochondria

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6
Q

which of the following is not a key player in apoptosis
1. caspase enzymes
2. lysosomes
3. mitochondria
4. ER

A

2

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7
Q

_____ typically clean up debris early

A

neutrophils

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8
Q

meshwork of tiny capillaries in early tissue repair is known as

A

granulation tissue

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9
Q

APAP causes cell death mainly in hepatic zone ______ by ______ effects
1. zone 1, complement
2. zone 3, complement
3. zone 1, mitochondrial
4. zone 3, mitochondrial

A

4

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10
Q

which of the following is not a recommended tx for anaphylactoid rxns
1. steroids
2. antihistamines
3. beta 2 agonists
4. epi

A

4

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11
Q

select all the conditions we should be cautious about use of decongestants in
1. diabetics
2. those with depression on medication
3. hyperthyroidism
4. CKD

A

all of the above

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12
Q

which of the following is not a form of management for decongestant toxicity
1 .oral activated charcoal
2. BZDs
3. phentolamine
4. BBs

A

4- worsens ischemia

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13
Q

ventricular dysrhythmias with decongestant OD is treated with

A

IV lidocaine

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14
Q

which is more likely to cause blood glucose and cardiac issues
1. pseudoephedrine
2. phenylephrine

A

1

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15
Q

in the misuse of antihistamines
1. CNS sx tend to resolve before cardiac manifestations resolve
2. activated charcoal may be used to decrease absorption
3. seizures may be treated with IV atropine
4. cardiac arrhythmias would avoid type 1A, 1C, III antiarrhythmics

A

4- can prolong QT interval- use hypertonic sodium bicarb sntead

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16
Q

how should refractory seizures from antihistamines be tx

A

propofol

17
Q

which of the following is not a change seen wih sedatives
1. drop in temperature
2. pinpoint pupils
3. ataxia
4. loss of some autonomic reflexes

A

2- no change in pupils

18
Q

what is the antidote for sedatie/ hypnotic toxidrome

A

flumazenil- but may cause withdrawal seizures/ arrhythmias

19
Q

which of the following is not an organ system primarily affected by opioids
1. CNS
2. ocular
3. cardio
4. respiratory

A

3

20
Q

which of the following is the least life threatening (based off pharmacology only)
1. methadone withdrawal
2. alcohol withdrawal
3. lorazepam withdrawal
4. all of the above are lethal

A

1- opioid withdrawal usually not life threatening