Microscopy Flashcards
Increased space between red blood cell indicates
Anaemia
What is the name of the centre of a normal RBC?
Central pallor
What is the normal size of the central size of a RBC?
1/3 of cells
Increased size of red cell pallor indicates ….
Hypochromic
What cell is used as a reference to see if the size of red cells is normal?
Normal red cell is the size of a lymphocyte nucleus
What causes tear drop red cells?
Autoimmune haemolytic anaemia or megaloblastic anaemia
What causes red cell fragmentation?
Mechanical destruction eg valve
What does a normal neutrophil appear like?
What does an abnormal neutrophil appear like?
Normal 3-5 nuclear segments
Abnormal hypersegmented nucleus, granulation, vacuolation
What is a Barr body?
Seen attached to segment of neutrophil nucleus, indicates XX phenotype X inactivation
What is a toxic neutrophil seen in?
Hypergranulation
Sepsis
What parasite infects inside red blood cells?
Malaria plasmodium
What causes cigar / pencil red cells?
Iron deficiency anaemia
What is poikilocytosis?
Red cells vary in shape
What is anisocytosis?
Red cells vary in size
What is acanthocytosis aka spur cells? (Appearance and causes)
Spikey appearance of red cell membrane
Alcoholism, Zieve syndrome, hepatitis, splenomegaly, hypothyroid, liver disease