Microscopy Flashcards
1
Q
Aristophanes (424 BC)
A
- convex lenses as burning lenses
- convex are capable of magnification
2
Q
Pliny (1st century AD)
A
- burning lenses to make therapeutic burns
- globe filled with water can magnify
3
Q
Alhazen (962-1038)
A
- transparent sphere can produce enlarged image
- lens of the eye produces image on retina
4
Q
Roger Bacon and Robert Grosseteste (13th century AD)
A
- describes what appears to be telescopes
- bacon described eyeglasses, burning lens, magnifiers
5
Q
When was compound microscope made
A
1590, 2 lenses at either end, about 10x mag
6
Q
Who invented the compound microscope
A
Hans Lippershey and Zacharias Janssen
7
Q
First magnified observations
A
- bees
- francisco stelluti
8
Q
Robert Hooke
A
- described elements of cork and called them “cells”
- didn’t understand the importance of cellular structure
- book “micrographia”
9
Q
Malpighi
A
- completed Harveys work
- saw capillaries from microscope between arterioles and veins
- observed embryonic development in chickens
- observed how form develops
10
Q
Epigeneticists
A
form develops from formlessness
11
Q
preformationists
A
form doesn’t develop, it grows
-little people in sperm cells
12
Q
Leeuwenhoek
A
- cloth merchant
- inspired by Hook’s “Micrographia”
- made his own microscope (one lens)
- 100x-200x magnification
- got published in Hooks Journal and became famous
13
Q
Leeuwenhoek’s results
A
- blood and circulation
- discovered capillaries (independent of Malphigi but after)
- saw RBC in salmon
- microorganisms in pepper
- generative cells: motile cells in gonorrhea
- proved spontaneous generation wrong (corn weevils)
14
Q
Why did microscopy slow down after the 1700’s?
A
- Leuweenhoek didn’t train any pupils
- microscope abberrations
- people said it was sacrilegious. If god wanted us to see these tiny things he would give us eyes
15
Q
When did microscopy enter biology to stay?
A
1900’s
