Chemistry Flashcards
Importance of Alchemy to Chemistry
- technique
- processes
- hardware
- analysis
- transformation
Deficiencies of Alchemy
- not quantitative
- no understanding
- mystical, not rationale
- failure
Paracelsus
- said that doctor must be a traveller (knowledge is experience)
- doctor without formal medical degree
- learnt about metallurgy
- publicly burned the works of Galen and Avicenna (thrown out of Basal for months)
What did Paracelsus believe
- medicine should focus on function not form
- iatrochem: life is chemical process and chem should be central to understanding human function and medicine (body has a mystical internal alchemist: archeus)
- illness is the result of defects in body chemistry, there should be a specific chemical therapy for every disease
what is metallurgy
physical and chemical properties of metals
Apothecaries
prepares and sells medicine/drugs
what was Paracelsus choice of drugs partially based on
- astrology (planets, metals, parts of body)
- docterine of signatures (herbs can be used to treat)
Paracelsus therapies
- clean wounds let them heal themselves
- treated syphilis with low doses of mercury
- used different metals: arsenic for skin problems
2 drugs that Paracelsus used
1) Laudanum: Alcohol version of opium. Prescribed to patients of all ages
2) Sweet Vitrol: di-ethyl-ether, used as a surgical anesthetic
What did Paracelsus think like
1) Chemist: precise measurements of starting material
2) Biochemist: realized that some things were fatal in high doses but useful in low doses. Thought that biochemical transformations took place in the body.
3) Mystic: thought that astrology was important when designing drugs
Van Helmont
- iatrochemistry: fav approach
- *understood the conservation of matter (dissolved metal in acid, weight stayed the same)
- believed that everything is made of water
Van Helmont Willow tree
- first experiment in plant physiology
- young tree gain 164 pounds in 5 years
- weight could not come from soil
- concluded that the rain water was absorbed by the surface of the tree
- quantitative experiment
Van Helmont Charcoal Experiment
- burned 62lbs of charcoal
- found that the products are 1 lb of ash and vapours
- doesn’t support the burning of a candle
- vapours with the same property were given off by burning alcohol and fermentation of wine
What did Van Helmont believe were all the same process of fermentation?
- food use by animals
- alcohol fermentation
- burning wood
Franciscus Sylvius
- said there was no archeus in iatrochemistry
- especially interested in acids and alkali’s
- digestion needs both pancreatic secretions and bile
- thought that illness was the result of an imbalance of acids and alkali’s
- invented medicine for kidney problems (distilled grain and juniper berries)