Microcirculation and Edema

Question 1

osmosis

Answer 1

movement of water across semipermeable membrane in response to concentration gradient

Question 2

penetrating solute

Answer 2

go through cell membrane
ex: gas

Question 3

nonpenetrating solute

Answer 3

charged
ex: anion, cation

Question 4

Jvol equation

Answer 4

Kf (forces favor filtration [Pcap +pi Int])- (forces oppose filtration [Pint + pi cap])

Question 5

pcap

Answer 5

inside capillary
hydrostatic pressure

Question 6

Pint

Answer 6

outside capillary
hydrostatic pressure

Question 7

Pi cap

Answer 7

oncotic pressure inside capillary
Albumin #1 contributer

Question 8

Pi int

Answer 8

oncotic pressure outside capillary

Question 9

vascular tone

Answer 9

how contracted smooth muscle is at any time
increase tone= increase constriction (resistance to bloodflow increases)

Question 10

do capillaries has vascular tone

Answer 10

no, they do not contain smooth muscle!!
arterioles and veins do not effect constriction/ dilation

Question 11

transcellular

Answer 11

goes from outside
needs help from transmembrane protein

Question 12

paracellular

Answer 12

in between adjacent cells
force driving movement is chemical gradient

Question 13

ascites

Answer 13

fluid
gas filled areas gone

Question 14

urticaria

Answer 14

hives filled with serous fluid

Question 15

non-cardiogenic pulmonary edema

Answer 15

fluid accumulates in the lungs, but not caused by the heart

Question 16

factors that affect Pcap

Answer 16

increase/ decrease blood pressure
viscosity
(pa-pv)
loss of blood

Question 17

factors that affect pi Int

Answer 17

toxins
blunt force trauma
lysis

Question 18

continuous capillary

Answer 18

found in muscle, nerve, and adipose tissue
coated pits

Question 19

fenestrated capillary

Answer 19

found in endocrine glands and glomerulus
fenestra covered with thin “diaphragm” like membrane

Question 19

sinusoidal (discontinuous) capillary

Answer 19

found in sinusoids
large fenestrations/ gaps
most leaky

Question 20

edema

Answer 20

interstitial and intracellular swelling
can be localized or widespread

Question 20

capillary permeability is affected by

Answer 20

hypoxia, drugs, pathological conditions