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Physiology > ANS > Flashcards

ANS Flashcards

1
Q

ANS

A

visceral efferent system
involuntary
has motor components

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2
Q

innervated

A

there is connection between terminal end nerve fiber and target tissue

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3
Q

dually innervated

A

structure receiving nerves from sympathetic and parasympathetic
most organs dually innervated have reciprocal activation

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4
Q

tactile sensation

A

tactile receptors in skin
density of receptors vary

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5
Q

proprioception

A

knowing body position in space @ time
internal receptors to allow brain to know where body is

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6
Q

nociception

A

can’t verbally express pain

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7
Q

lower motor neuron

A

only motor neuron that leaves brainstem

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8
Q

calcium

A

all skeletal muscles mediated by
all exocytotic events mediated by

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9
Q

flacid paralysis

A

paralysis of skeletal muscles, could be caused by presynaptic Ach accidently
-always cause post synaptic response but doesn’t always cause contractions
Nicotinic type 1?

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10
Q

acetylcholine esterase

A

digests ach

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11
Q

cholineaceytyl CoA transfertase

A

joins acetyl CoA and choline together to make Ach

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12
Q

Nm receptors

A

transmembrane
excitatory
ionotropic
sense “tissue” damage
–results in depolarization but no AP

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13
Q

ionotropic

A

Ach causes channels to open and release ions

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14
Q

graded potential

A

summate/ add up

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15
Q

EPSP

A

excitatory post synaptic potential
causes depolarization, carried by sodium
in skeletal muscle

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16
Q

IPSP

A

inhibitory post synaptic potential
downregulates next nerve fiber

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17
Q

spacially indiscrete

A

+ chronotropism
+ inotropism
increase BP
—- stimulates multi organ. multi tissue activation

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18
Q

reticellular formation

A

place in brain that makes you hyper aware of surroundings

19
Q

epi

A

from adrenal medulla
increase glycogen phosphorylase (liver and skeletal muscle)

20
Q

N2 receptor

A

ionotropic
ligand gated depolarization
increase density of V-gated Na+ channels

21
Q

to make NE

A

need tyrosine or phenylalanine
-tyrosine carboxylase enzyme needed

22
Q

DOPA

A

dopamine
-substrate for enzymes that make NE and epinephrine

23
Q

PNMT

A

phenylethanolamine N- methyl transferase
enzyme that converts NE to epinephrine

24
Q

muscarinic receptors

A

g-protein

25
Q

interganglionic commissural fiber

A

ganglionic chain in sympathetic

26
Q

PNS

A

long then short for 2 projection neuron
only muscarinic receptors

27
Q

Sympathetic nervous system

A

short then long for 2 projection neuron
alpha and beta adrenergic receptors
–synapse at adrenal medulla or ganglion-> organ

28
Q

E:NE

A

85:15

29
Q

NE route

A

NE-> PNMT-> bloodstream-> hormone

30
Q

metabotropic receptor

A

EX: muscarinic
heterotrimeric (3 different parts)
-receptor to Ach, alows for dissociation of g-protein

31
Q

ionotropic receptor

A

EX: nicotinic
Ach attach to receptor
-ions moving
-find between 1st and 2nd synapse

32
Q

chemical messenger

A

biogenic amines (catacholamines)

33
Q

amino acid neurotransmitters

A

GABA
-inhibitory NT
-brain and spinal cord
-receptors multisubunit
-induce CL current (hyperpolarize)

34
Q

indirect gating

A

use second messenger

35
Q

direct gating

A

ach to receptor, ions flow

36
Q

signal transduction

A

GTP binding proteins
-couple hormone receptors to effector molecules
-hetertrimeric
G proteins can be stimulatory or inhibitory

37
Q

6 step plan

A

recognition, transduction, transmission, modulation of effector, response, termination

38
Q

somatic nervous system

A

one neuron, Type 1 nicotinic receptor
skeletal muscle!!

39
Q

propranolol

A

beta blocker (antagonist) for NE and epi and indirect alpha agonist

40
Q

phentolamine

A

alpha antagonist, induce vasodilation

41
Q

atropine

A

block ach, anti muscarinic

42
Q

dobutamine

A

beta-1 agonist (stimulates), increase HR

43
Q

dexmetetomadine

A

alpha-2 agonist
-activate g-protein in brainstem to inhibit NE

44
Q

prazosin

A

alpha antagonist, induce vasodilation to decrease HR

Physiology (11 decks)

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