microbiome Flashcards

1
Q

what is a negative aspect of the microbiome?

A

decreases lean mass

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2
Q

we know that skeletal muscle mass is decreased in mice that do not have a microbiome thus what can we hypothesize?

A

factors within the microbiome promote muscle mass

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3
Q

muscle mass is decreased following _____ treatment in mice

A

antibiotic

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4
Q

gut bacterial species that positively affect skeletal muscle mass

A

lactobacillus reuteri/gasseri

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5
Q

________ which are produced by bacterial fermentation of dietary fiber, increase muscle mass

A

short chain fatty acids

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6
Q

butyrate _______ skeletal muscle mass in aged mice

A

increases

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7
Q

muscle mass is decreased in conjunction with reduced fecal and plasma SCFAs

A

yep

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8
Q

indoxyl sulfate negatively/positively affects muscle development

A

negatively

more studies are needed to clarify the in vivo role of IS on muscle mass

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9
Q

poor muscle composition is associated with insulin resistance, reduced mobility and physical function, frailty and an increased all cause mortality risk

A

yep

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10
Q

muscle strength and swimming endurance capacity are improved in response to probiotic supplementation

A

yep

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11
Q

what will improve muscle strength in young GFM

A

short chain fatty acids

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12
Q

what so special about atheletes and their microbiomes?

A

have higher fecal SCFAs

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13
Q

guys hypothesis

A

gut bacteria are associated with and are causatively involved in mechanisms related to the maintenance of lean mass and physical function in older adults

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