microbiome Flashcards
what is a negative aspect of the microbiome?
decreases lean mass
we know that skeletal muscle mass is decreased in mice that do not have a microbiome thus what can we hypothesize?
factors within the microbiome promote muscle mass
muscle mass is decreased following _____ treatment in mice
antibiotic
gut bacterial species that positively affect skeletal muscle mass
lactobacillus reuteri/gasseri
________ which are produced by bacterial fermentation of dietary fiber, increase muscle mass
short chain fatty acids
butyrate _______ skeletal muscle mass in aged mice
increases
muscle mass is decreased in conjunction with reduced fecal and plasma SCFAs
yep
indoxyl sulfate negatively/positively affects muscle development
negatively
more studies are needed to clarify the in vivo role of IS on muscle mass
poor muscle composition is associated with insulin resistance, reduced mobility and physical function, frailty and an increased all cause mortality risk
yep
muscle strength and swimming endurance capacity are improved in response to probiotic supplementation
yep
what will improve muscle strength in young GFM
short chain fatty acids
what so special about atheletes and their microbiomes?
have higher fecal SCFAs
guys hypothesis
gut bacteria are associated with and are causatively involved in mechanisms related to the maintenance of lean mass and physical function in older adults