microbiology of dermatology Flashcards
what commensals should you not treat
staph epidermis, diphtheroid
examples of common skin infections due to bacteria
boils and carbuncles, impetigo, infected eczema
where is staph aureus found
on skin and mucous membranes
how does staph aureus grow
best aerobically but can grow anaerobically
examples of staph A virulence factors
capsule - antiphagocytic, fibrinogen binding system for adhesion and coagulase to clot plasma
investigations for suspected staph A
swab +/- blood cultures
management of normal staph A
flucoxacillin
management of MRSA
doxycycline, vancomycin
complications of staph A
toxic shock syndrome, panton-valentine leukocadin, scalded skin syndrome, enterotoxin
what is the presentation of TSS
some strains release harmful toxins -> tocinoses
- diffuse macular rash, fever and hypotension
what does panton- valentine leukocadin do
kills leukocytes
what does enterotoxin cause
food poinoning
what is strep pyogenes
group A strep
where is strep pyogenes found
in throat but can adhere to skin
group A strep haemolysis
beta heamolysis
what can beta haemolysis cause
tissue/ cell destruction
what classification system is used for serotyping surface antigen
lancefield system
what protein antigens cause severe disease
M3 and M18
what is the management of strep pyogenes infection
flucloxacillin
complications of strep pyogene
necrotizing fascitis - type 2, toxic shock, cellulitis
desrcibe necrotsing fascitis
invasive starins rapidly destroy connective tissue, life threatening and requires immediate surgical debridement
how to treat leg ulcers
if no infection signs - no swabs and no antibiotics
