Microbiology - MSK infections 2 Flashcards

1
Q

What are the signs/symptoms of acute osteomyelitis ?

A
  • fever or chills
  • malaise (discomfort)
  • At the infection site, pain, limited range of motion, and redness, warmth or swelling.
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2
Q

What are the signs/symptoms of chronic osteomyelitis ?

A
  • Chronic low-grade fever
  • chronic localized pain
  • A draining sinus tract that has been present for months or even years

sinus tract is a narrow opening or passageway underneath the skin that can extend in any direction through soft tissue and results in dead space with potential for abscess formation.

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3
Q

What is the most common cause of osteomyelitis in general ?

A

Staph.aurues

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4
Q

What is the antibiotics given for acute osteomyelitis or septic arthritis ?

(hint it is the exact same regime)

A

IV Flucloxacillin

If penicillin allergic - clindamycin

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5
Q

What is the antibiotics given for chronic osteomyelitis ?

A

Oral flucloxacillin

If MRSA or penicillin allergy then doxycycline or co-trimoxazole

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6
Q

What is the treatment for MRSA osteomyelitis ?

A

IV Vancomycin

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7
Q

What is pyomyositis ?

A

Is a bacterial infection of the skeletal muscles which results in a pus-filled abscess.

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8
Q

What is tetanus and what is it caused by ?

A
  • A serious but rare condition caused by bacteria getting into a wound.
  • Clostridium tetani
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9
Q

What are the characteristic signs/symptoms of tetanus ?

A
  • prodrome fever, lethargy, headache
  • trismus (lockjaw)
  • risus sardonicus
  • opisthotonus (arched back, hyperextended neck)
  • spasms (e.g. dysphagia)
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10
Q

What is the treatment of tetanus ?

A
  • —Surgical debridement.
  • —Supportive measures.
  • IM human tetanus immunoglobulin for high-risk wounds (e.g. compound fractures, delayed surgical intervention, significant degree of devitalised tissue)
  • metronidazole is now preferred to benzylpenicillin as the antibiotic of choice
  • Booster vaccination……..toxoid.
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