Microbiology 154 Exam 3 Review Flashcards
A molecular clock for evolution is based on
a. Fossil records for organisms
b. Cellular structures of organisms
c. Nucleotide sequences in the genomes of organisms
d. Enzymatic activities of organisms
c. Nucleotide sequences in the genomes of organisms
Woese developed the three-domain system based on differences organisms’
a. Cell morphologies
b. rRNA sequences
c. Gram stain reactions
d. habitats
b. rRNA sequences
In the scientific name Staphylococcus aureus, Staphylococcus is the
a. Class
b. Genus
c. Specific epithet
d. Family
b. Genus
A prokaryotic species is defined as a
a. Population of cells with similar characteristics
b. Population of cells with different characteristics
c. Group of closely related organisms that can interbreed
d. Group of organisms that are not composed of cells
a. Population of cells with similar characteristics
Treating DNA from different bacteria with the same restriction enzyme followed by separation of the fragments by electrophoresis is known as
a. DNA base composition
b. DNA fingerprinting
c. The nucleic acid amplification test (NAAT)
d. Ribotyping
b. DNA fingerprinting
A person who has measles will develop ________ immunity.
a. Naturally acquired active
b. Naturally acquired passive
c. Artificially acquired active
d. Artificially acquired passive
a. Naturally acquired active
Plasma cells are formed after the proliferation of which type of cell?
a. B cell
b. T cell
c. Dendritic cell
d. Macrophage
a. B cell
Generally, antibodies recognize and interact with specific regions on antigens called
a. PAMPs
b. Haptens
c. Epitopes
d. Active sites
c. Epitopes
Phagocytes contain ________ that allow attachment of pathogens.
a. Antibodies
b. Toll-like receptors
c. Spikes
d. PAMPs
b. Toll-like receptors
During ingestion, pseudopods of a phagocyte fuse, surrounding the microorganism in a(n)
a. Phagosome
b. Granule
c. Inclusion body
d. Histiocyte
a. Phagosome
Which of the following is an example of the epidemiological triangle?
a. a bat infecting a human with ebola virus
b. a disease carried from one continent to another where it then becomes prevalent
c. locating three cases of a diseases to estimate the center of the outbreak
d. an opportunistic pathogen like clostridium difficile infecting an immune-compromised patient
a. a bat infecting a human with Ebola virus
which of the following statements about innate immunity is FALSE?
a. the innate immune system recognizes general characteristics of foreign organisms
b. the innate system lacks “memory” and does not respond more vigorously when a foreign organism invades the body second time
c. the innate immune system is a surveillance system that is induced when an infection occurs
d. the innate immune system does not confer long-lasting immunity
c. the innate immune system is a surveillance system that is induced when an infection occurs
what best describes an endemic disease?
a) a disease that occurs only occasionally
b) a disease constantly present in a population
c) a disease acquired by many people in a given area in a short time
d) a worldwide epidemic
b. a disease constantly present in a population
Which of the following are early examples of epidemiology?
a) John Snow collecting cholera surveillance data and shutting down the Broad Street pump in London
b) Ignaz Semmelweis forcing doctors and interns to wash their hands in his surgical ward to reduce the incidence of puerperal fever
c) Alexander Fleming demonstrating that Penicillium rubens exuded a substance with antibiotic properties
d) (a) and (b)
e) All of the above
d. (a) and (b)
Which of these diseases is zoonotic?
a) Plague
b) Influenza A
c) Measles
d) HIV
a) plague
Which of the following statements about macrophages is FALSE?
a) Macrophages have pattern recognition receptors (PRRs) that recognize molecules that are broadly shared by pathogens (PAMPS) but distinguishable from host molecules.
b) The LPS of Gram negative bacteria and teichoic acids of Gram positive bacteria are examples of PAMPs.
c) Macrophages stimulate the production of antibodies that are specific for a particular pathogen
d) Macrophages can ingest, kill and digest invading microorganisms
c) Macrophages stimulate the production of antibodies that are specific for a particular pathogen
Antibodies
a) are very specific and can identify a particular microbe with high precision.
b) are produced in response to vaccines
c) function as opsonins and enhance phagocytosis
d) all of the above.
d) all of the above
Which of the following help protect humans and other animals against infectious diseases?
a) the adaptive immune system
b) the innate immune system
c) mechanical defenses
d) only (a) and (b)
e) all of the above (a, b and c)
e) all of the above (a, b, and c)
Which part of Ebola virus is the target of neutralizing antibodies?
a) glycoprotein
b) DNA polymerase
c) nucleocapsid
d) lipid envelope
e) viral genome
a) glycoprotein
Which of the following statements about vaccines is FALSE?
a) vaccines cause antibodies to be produced that specifically target a specific pathogen
b) vaccines are sometimes based on attenuated live organisms
c) vaccines cause autism
d) vaccination is a highly effective way to prevent infectious diseases
c) vaccines cause autism
Immunological ‘memory’
a) helps the immune system respond more rapidly to infectious agents
b) is a key reason why vaccines are effective
c) is usually not effective
d) only (a) and (b)
e) all of the above (a, b and c)
d) only (a) and (b)
In recent years there have been an increased incidence of measles in the United States. This is thought to be largely because
a) antibiotic resistance has become more wide-spread
b) people travel abroad more than they used to
c) an increasing number of people have not been vaccinated against measles
d) the average age of people in the United States has decreased
c) an increasing number of people have not been vaccinated against measles
Which of the following statements about tuberculosis is TRUE
a) the increased incidence of antibiotic resistance in Mycobacterium tuberculosis is an emerging health care crisis.
b) it has only recently become a common disease
c) has become much more common in the United States because the incidence of HIV has increased
d) it is only found in people with HIV
a) the increased incidence of antibiotic resistance in Mycobacterium tuberculosis is an emerging health care crisis.
Which of the following statements is FALSE
a) the gut microbiome ‘communicates’ with the human brain
b) the gut microbiome can be dramatically affected by antibiotics
c) the gut microbiome does not change much after an individual is born d) none of these statements are false
d) none of these statements are false
People living with HIV are 20 to 30 times more likely to develop tuberculosis than people without HIV. Why?
a) they are likely to be socioeconomically disadvantaged and do not have ready access to adequate health care
b) their immune systems can not function as well as those of healthy individuals
c) they are more likely to be exposed to people infected by Mycobacterium tuberculosis
d) all of the above
b) their immune systems can not function as well as those of healthy individuals
Which of the following is not true about oxygen
a) Is always used as a terminal electron acceptor in bacterial metabolism
b) Required for strictly aerobic bacteria
c) Can be toxic or lethal to some organisms
d) Toxicity mostly due to the production of superoxide radicals that are powerful oxidizing agents
e) Aerobic bacteria can protect themselves but strict anaerobes can not
a) Is always used as a terminal electron acceptor in bacterial metabolism
A metagenome
a) consists of all the mRNA molecules in a single species
b) consists of all the genome sequences present in a microbial community
c) consists of all the mRNA sequences in a microbial community
d) is determined by the DNA sequence of a bacterial genome
b) consists of all the genome sequences present in a microbial community
“Cultivation-independent” methods
a) are used once the organisms in a microbial community have been isolated and pure cultures have been obtained
b) are commonly used to determine microbial community structure and function
c) only provide information about the genome sequences of the bacterial species present in a community
d) all of the above are true statements
b) are commonly used to determine microbial community structure and function
c) only provide information about the genome sequences of the bacterial species present in a community
The human microbiome
a) includes all the bacterial species that reside in the gut and elsewhere in and on your
body
b) includes thousands of bacterial species
c) markedly varies between individuals
d) all of the above are true
d) all of the above are true
The vaginal pH of healthy women
a) is always less than 4.5
b) is almost the same in all reproductive age women
c) is the same among females of all ages
d) is usually acidic because of lactic acid produced by bacteria
e) these are all true statements
d) is usually acidic because of lactic acid produced by bacteria
Bacterial communities in the human vagina
a) are comprised of many bacterial species
b) have high numbers of bacterial cells
c) vary over time in almost all reproductive age women
d) all of the above are true statements
d) all of the above are true statements
The degree of pathogenicity of an organism is known as the
a) antigenicity.
b) toxigenicity.
c) virulence.
d) cytopathic effect.
c) virulence.
Antibiotics that kill bacteria are
a) referred to as bactericidal antibiotics
b) referred to as bacteriostatic antibiotics
c) not effective in treating infections
d) commonly used because they also kill eukaryotic cells
a) referred to as bactericidal antibiotics