Microbiology Flashcards

1
Q

How do you know it’s an anaerobe?

A

Gas, bad odor

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2
Q

What makes an adequate sputum sample?

A

25 leukocytes per low power field

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3
Q

What bug causes acute bacterial endocarditis?

A

Strep viridians (attacks damaged valves)

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4
Q

How do you diagnosed Rheumatic Fever?

A

Need at least 2 “SPECC”

Subcutaneous nodules
Polyarthritis
Erythema Marginatum (red margins)
Chorea (Sydenham's)
Carditis (MS>AS>TS) "MAT"
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5
Q

What are the only Gram - diplococci?

A

Neisseria

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6
Q

What is the only Gram + diplococci?

A

Streo pneumo

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7
Q

What bugs cause heart block onfections?

A

“Dont TeLL Chaga”

Diphtheria
Typhoid fever (salmonella typhii)
Legionella
Lyme disease
Chagas disease (Whipple's)
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8
Q

What are the IgA protease bugs?

A

Strep pneumo
H. influenza
Neisseria catt

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9
Q

What do the IgA protease bugs cause?

A

Sinusitis, otitis media, pneumonia, bronchitis

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10
Q

What are the simple Gram-bugs?

A

“simple HE”
H-influenza
E.coli

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11
Q

What are the atypical (no cell wall) bacteria?

A
"CLUMsy"
Chlamydia
Legionella
Ureaplasma
Mycoplasma
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12
Q

What is the only Gram + endotoxin?

A

Listeria

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13
Q

What are the Gram - exotoxins?

A

H influenza, Bordetella Pertussis

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14
Q

What are the spore forming Gram + bacteria?

A

Bacillus anthracis, Clostridium botulinum

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15
Q

What bugs cause walking pneumonia?

A
"Come My Love for a walk?
0-2 mo: Chlamydia pn
10-30 y: Mycoplasma pn
>40 y: Legionella pn
AIDS/Premies: Pneumo Jirovecii
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16
Q

What causes Cryoglobulinemia?

A
"I AM HE"
Influenza
Adenovirus
Mycoplasma
Hep B, C
EBV
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17
Q

What are the Silver Stainers?

A
"HaLV-C=Comma"
H. pylori
Listeria
Vibrio
Campylobacter
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18
Q

What bacteria cause diarrhea

A

“CBS”
Clostridium
Bacillus cereus
Staph aureus

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19
Q

What are the Gram - capsules?

A

“Some Killers Have Pretty Nice Capsules”

Salmonella
Klebsiella
H influenza B
Pseudomonas
Neisseria
Citrobacter
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20
Q

What is the Gram + Capsule?

A

Strep Pneumo

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21
Q

What are the Urease + bugs?

A
"Urease PPUNCH"
Proteus
Pseudomonas
Ureoplasma
Nocardia
Cryptococcus
H Pylori
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22
Q

What bugs cause Monocytosis?

A
"STELS" 
Syphilis
TB
EBV
Listeria
Salmonella
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23
Q

What are the big Mama Anaerobes?

A

Bacteroides fragilis
Strep Bovis
C. septicum

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24
Q

What bugs disrupt G proteins?

A

Pertussis: inhibits Gi
Cholera: Stimulates Gs
E. coli: Stimulates Gs

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25
What bacterias causes UTIs and prostatitis?
E.coli Proteus Klebsiella Pseudomonas
26
What bug is associated w/cat scratch?
Bartonella henselae
27
What bug is associated w/cat saliva?
Pasturella multocida
28
WHat bug is associated w/ cat pee?
Toxoplasmosis
29
What bug is associated w/cat caca?
Toxocara cati
30
What disease are caused by the Ixodes Tick?
Lyme disease -bull's eye lessions Babesiosis - hemolytic anemia Ehrlichiosis - puncture near eye
31
What bug causes hospital abscesses?
Day 1-3: Staph aureus - lots of O2 Day 4-7: Strep viridans: no enzymes Day >7: Anaerobes - PMNs
32
What kind of patients does Staph and Pseudomonas like to attack?
DM Cystic fibrosis pt Burns pts Neutropenic pts
33
What disease have granulomas?
``` TB Sarcoidosis Syphilis Histiocytosis X The -ellas ```
34
What disease provide malaria protection?
Sickle cell: AAs | G-6PD: Mediterraneans
35
What bug causes multiple liver abscesses?
Entamoeba histolytica
36
What bug causes multiple cerebral abscesses?
Citrobacter
37
What has multiple lung aneurysms?
Osler-Weber-Rendu
38
What bugs cause Loeffler syndrome?
``` "NASSA" Necator americanus Ancylostoma duodenale Schistosomiasis Strongyloides Ascaris lumbricoides ```
39
What is the symptom of Loeffler syndrome?
Pulmonary eosinophilia
40
What is PIE syndrome?
Pulmonary Infiltrate w/ Eosinophilia
41
What disease have PIE syndrome?
Aspergillus, Loeffler's, Churg-Strauss
42
What disease does Coxsackie A cause?
Hand-foot-mooth disease
43
What disease does Coxsackie B cause?
Endocarditis, DM type 1
44
What bugs cause Meningitis?
0-2mo: "baby BEL" Group B strep E coli Listeria >2mo: Strep pneumo 10-21y/o: N. meningitidis
45
What are the CSF lab vales for Meningitis?
PMNs-> bacteria T cells/MP->nonbacterial Normal glucose -> viral
46
What does the Hep B Core Ag tell you?
Gone before pt has symptoms (2 mo)
47
What does the core Ab tell you?
Past infection
48
What does the surface Ag tell you?
Current infection
49
What does the surface Ab tell you?
Vaccination has occurred
50
What does the E Ag tell you?
Transmissibility/infectivity
51
What does the E Ab tell you?
Low transmissibility
52
What antibody shows past Hep A infection?
IgG
53
What antibody shows current Hep A infection?
IgM
54
What type of people does Hep E like to infect?
Pregnant women. Asians
55
What is associated with Staph aureus?
Cellulitis, dairy products, gold pigment, endocarditis, styes, hordeolum (on eyelid)
56
What is associated with Strep pyogenes?
"LINES", ASO, hyaluronic acid capsule
57
What is associated with Staph epidermidis?
Central lines, VP shunts, white pigment
58
What is associated w/ Propionibacterium?
Acne, Progesterone=> propionic acid
59
What is associated w/Pateurella?
Cat/dog saliva => cellulitus w/lymphadenitis
60
What is associated w/Staph saprophyticus?
Female UTIs, honeymooners cystitis
61
What is associated w/ Hemophilus aegyptus?
Swollen eyeball w/pus
62
What is associated w/Francisella tularensis?
Ulcers at rabbit or deer tick bite site (Tx: Streptomycin)
63
What is associated with Pseudomonas aeruginosa?
Otitis externa, ecthyma granulosum, loves rubber, whirlpool folliculitis, ADP ribosylates EF-2
64
What is associated w/Streptococcus pneumoniae?
Otitis media, red bulging tympanic membrane
65
What is associated w/ Fusobacterium?
Painful mouth ulcers, gum pus, Vincents angina
66
What is associated w/Strep mutans?
Dental Cavities
67
What is associated w/ Strep viridans?
Subacute bacterial endocarditis, green pigment
68
What is associated w/Strep salivarius?
Cold agglutinin test
69
What is associated w/Strep pyogenes?
Rheumatic fever, strain 12=>PSGN
70
What is associated w/ Group C Strep?
Pharyngitis
71
What is associated w/ Corynebacyerium diphtheriae?
Chinese letters, gray pseudomembrane, suffocation, ADP ribosylates EF2, heart block, Elek test
72
What is associated w/ Strep pneumonia?
Gram + diplococci, rusty sputum, IgA protease, vaccine covers 23 strains
73
What is associated w/ H influenza?
Gram - pleomorphic rod, Factors V/X, 5 C-ribose capsule, B-type:meningitis, epiglottitis, sepsis
74
What is associated w/ N Catarrhalis?
Loves mucus-> attacks respiratory tract
75
What is associated w/ Chlamydia psittaci?
Parakeets, parrots
76
What is associated with Chlamydia pneumonia?
Staccato coughing, elementary and reticulate bodies
77
What is associated with Mycoplasma pneumonia?
Bullous myringitis, ground glass CXR, P1 protein, erythema multiforme
78
What is associated w/ Legionella pneumonia?
AC ducts, silver stains lung, CYEA, pontiac fever, Legionnaire's pneumonia
79
What is associated with Pnuemocystis Jiroveciinia?
AIDS, premies, rusty sputum, silver stains lung, ^ LDH (Tx: steroids)
80
What is associated with Clostridium botulinum?
Canned food, honey, inhibits Ach release, resp failure, stool toxin (Tx: Penicillin)
81
What is associated with Clostridium tetani?
Rusty nail wounds, inhibits Gly release, resp failure, risus sardonicus, tennis, racquet shape
82
What is associated with Bordetella pertussis?
Whooping cough, ADP ribosylates Gi
83
What is associatedw/Bacillus antracis?
Black eschar, woolsorter's lung disease, D-Glu, boxcar-like spore (Tx: Ciprofloxacin)
84
What is associated with H pylori?
Duodenal ulcers
85
What is associated with Salmonella?
Raw chicken & eggs, tutles, rose typhoid spots, H2S, sickle cell osteomyelitis
86
What is associated w/ Campylobacter jejuni?
Raw chicken & eggs, very bloody diarrhea, inactivated by gastric juice, Guillain-Barre, seagull -shape
87
What is associated with clostridium perfringes?
Holiday ham & turkey, DM gas gangrene, soil/feces
88
What is associated w/ Bacillus cereus?
Fried rice, pre-formed toxin
89
What is associated with Listeria monocytogenes?
Raw cabbage, hot dogs, spoiled milk, migrant workers => heart block, meningitis, abortions
90
What is associated w/ Vibrio parahaemolyticus?
Raw fish
91
What is associated with Actinomyces?
Face fistulas, sulfur granules
92
What is associated w/ Vibrio vulnificus?
Raw oysters, cellulitis in swimmers cuts
93
What is associated with Shigella?
Day care outbreaks => seizures, destroys 60 S ribosome, infects M cells
94
What is associated with Vibrio Cholera?
Rice water diarrhea, ADP ribosylates Gs
95
What is associated w/ Clostridium difficile?
Explosive diarrhea= pseudomembranous colitis
96
What is associated with Yersinis enterolitica?
Presents like appendicitis + Reiter's, bloody diarrhea
97
What is associated w/ Strep bovis?
Colon cancer, black pigment
98
What is associated with Clostridium septicum?
colon cancer
99
What is associated with ETEC?
Traveler's=> rice-water diarrhea
100
What is associated with EHEC?
Hemmorrhagic=> renal failure
101
What is associated w/ EIEC?
Inflammatory=> loose stool
102
What is associated w/ EPEC?
Pathogenic=> newborn diarrhea
103
What is associated w/ E. coli?
Raw hamburger, ADP ribosylates Gs, verotoxin, HUS
104
What is associated w/ Proteus mirabilis?
Staghorn calculus, UTI (Tx: Norfloxacin)
105
What is associated w/Klebsiella pneumonia?
Alcoholics, currant jelly sputum, UTI lung fissure
106
What is associated w/ Staph saprophyticus?
Young & college girls UTIs
107
What is associated with N meningitides?
DIC, pili, releases toxin in log phase
108
What is associated with Brucella?
farmers/vet, spiking fever 5x/day, animal placentas
109
What is associated w/ R. rikettsii?
Ticks=> Rocky mountain spotted fever
110
What is associated w/ R. akari?
Mites=> fleshy papules
111
What is associated w/ R typhi?
Fleas, starts in armpit
112
What is associated w/ R. prowazekii?
Lice, starts on body
113
What is associated w/ R tsutsugamushi?
Mites=> scrub typhus
114
What is associated with Coxiella burnetti?
Dusty barn=> Qfever
115
What is associated w/ Yersinia pestis?
Rats, fleas=> bubonic plague
116
What is associated with Bartonella henselae?
Cat scratch => single painful lymph node, silver stains
117
What is associated w/ bacteroides fragilis?
Post-op bowel abscess, grows in blood clots
118
What is associated w/ Chlamydia trachomatis?
Neonatal inturned eyelashes/cornea ulcers
119
What is associated w/Neisseria gonorrhea?
Pili, urthritis, tenovitis, septic arthritis