Microbe Control Flashcards
Understand how microbe growth is controlled by various agents and processes
What is the goal of sterilization?
The destruction of Bacterial endospores
Which organism is the most resistant?
Bacterial Endospores
Which organisms are the least resistant?
Enveloped Viruses
Which agents have the widest target range?
Heat and Radiation
Agents that are selective in their cellular targets tend to be…
more restricted in effectiveness
usually target a single cellular component
How many antimicrobial targets are there?
4
What are the targets for antimicrobials?
- Cell wall
- Cell Membrane
- Protein
- Nucelic Acids
How do antimicrobials interfere with cell walls?
Blocking synthesis
Digesting the cell wall
How do antimicrobials interfere with cell membranes?
bind to lipid layer, make a hole and disrupt cellular homeostasis
How do antimicrobials interfere with proteins
Causes denaturing
Prevents interaction between protein active site and substrate
How do antimicrobials interfere with nucleic acids
Acts as a mutagen
Keeps microbes from making proteins
What agents disrupt cell walls?
Chemicals
detergents
Alcohols
Surfactants
What agents disrupt cell membranes?
Detergents
What agents disrupts proteins?
Moist Heat
Alcohol
Phenolics
What agents disrupt nucelic acids?
Formalydhyde
Radiation
Ethelyne Oxide