Microbe Control Flashcards

Understand how microbe growth is controlled by various agents and processes

1
Q

What is the goal of sterilization?

A

The destruction of Bacterial endospores

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2
Q

Which organism is the most resistant?

A

Bacterial Endospores

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3
Q

Which organisms are the least resistant?

A

Enveloped Viruses

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4
Q

Which agents have the widest target range?

A

Heat and Radiation

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5
Q

Agents that are selective in their cellular targets tend to be…

A

more restricted in effectiveness

usually target a single cellular component

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6
Q

How many antimicrobial targets are there?

A

4

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7
Q

What are the targets for antimicrobials?

A
  1. Cell wall
  2. Cell Membrane
  3. Protein
  4. Nucelic Acids
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8
Q

How do antimicrobials interfere with cell walls?

A

Blocking synthesis

Digesting the cell wall

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9
Q

How do antimicrobials interfere with cell membranes?

A

bind to lipid layer, make a hole and disrupt cellular homeostasis

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10
Q

How do antimicrobials interfere with proteins

A

Causes denaturing

Prevents interaction between protein active site and substrate

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11
Q

How do antimicrobials interfere with nucleic acids

A

Acts as a mutagen

Keeps microbes from making proteins

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12
Q

What agents disrupt cell walls?

A

Chemicals
detergents
Alcohols
Surfactants

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13
Q

What agents disrupt cell membranes?

A

Detergents

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14
Q

What agents disrupts proteins?

A

Moist Heat
Alcohol
Phenolics

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15
Q

What agents disrupt nucelic acids?

A

Formalydhyde
Radiation
Ethelyne Oxide

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16
Q

Six (6) methods of physical control

A
Heat
Cold
Desiccation
Radiation
Filtration
Osmotic Pressure
17
Q

What are the types of heat?

Which heat is sterile?

A

Moist heat and Dry heat

Dry Heat

18
Q

Microbe heat resisters are

A

Spores

19
Q

Types of moist heat

A

Boiling
Pasturization
Non-pressure steam
Pressure steam

20
Q

Is cold microstatic or microbial

A

Microstatic

21
Q

Dessication is synonomous with

A

Dessication

22
Q

Radiation types

A

Ionizing radiation

Non-ioninzing Radiation

23
Q

HEPA filters, filter

A

air

24
Q

Chemical control agents have _____ action in _______ concentration

A

Rapid; low

25
Q

Chemical control agents must be ______ in water

A

soluble

26
Q

Chemical control agents must have a ______ microbial range but be ______ to humans

A

broad; nontoxic

27
Q

Should chemical agents be able to penetrate inanimate objects?

A

yes

28
Q

Chemical agents should sanitize, deodorize, and be readily available and affordable?

A

Yes

29
Q

What factors determine germicidal activity

A

Chemical concentration

Length of exposure

30
Q

What are the levels of chemical decontamination

A

High- level germicide
Intermediate
Low

31
Q

What are characteristics of low level germicides

A

kills vegatative microbes

some viruses

32
Q

What are characteristics of intermediate level germicides

A

Kills FUNGAL spores
kills resistant pathogens
kills viruses

33
Q

What is characteristic of high level germicides

A

killing endospores

34
Q

If a germicide can kill endospores it is assumed that it can kill most other microbes

A

yes

35
Q

What are the groups of germicidal sterilizers

A
Chlorine
Iodine
H2O2
Aldehydes
gaseous sterilants
36
Q

What are groups of germicidal disinfectants

A
Phenol
Chlorohexidine
Alcohol
Detergents
Heavy Metal compounds