micro lecture 1 Flashcards
1
Q
What does selective toxicity of an antimicrobial drug mean?
A
The antimicrobial drug selectively kills or inhibits the growth of microbial targets while causing minimal or no harm to the host.
2
Q
What is a therapeutic dose defined as?
A
Dose level for successful treatment of infection.
3
Q
Define “toxic dose” of a drug.
A
Dose level of drug in which the agent is too toxic for host.
4
Q
True or False.
Antibacterial drugs that disrupt microbial functions, tend not to be found in eukaryotic cells
A
True.
5
Q
How many classes of mechanism of action (MOA) for antibacterial agents are there?
A
5
6
Q
What are the 5 classes of mechanism of action (MOA) for antibacterial agents?
A
- Inhibitors of cell wall synthesis
- Disruptors of cell wall/membrane
- Protein synthesis inhibitors
- Metabolic antagonists
- Nucleic acid synthesis/manipulation
inhibitors
