micro bacteria Flashcards
1
Q
m. leprae: reservoir, transmission, risks
A
- infected humans, some animals
- trasmitted through aerosols, long term contact
2
Q
m. leprae: pathogenesis
A
cell wall evades host response
3
Q
m. leprae: ID, treatment
A
- ID typical lesions, can use acid-fast stain
- treat w/ combination of antibiotics: dapsone, rifampin, clofazimine
4
Q
leprosy: progression, symptoms
A
- slow progression, affecting skin, nerves, mucus membranes
- tuberculoid version w/ minimal organisms causes peripheral nerve damage. immune response is normal cellular
- lepromatous: profuse growth, organisms in lesions, disseminated, T cell anergy
5
Q
m. tuberculosis: pathogenesis
A
- bacteria enter alveoli and are phagocytosed by macrophages
- migrate to surrounding alveoli, lymph nodes
- recruit other immune cells
- isolated by tubercle formation
6
Q
m. tuberculosis: ID , treatment
A
- ID w/ PPD test (latency), acid-fast stain of sputum is fastest
- treated w/ RIPE combo
7
Q
vibrio cholerae: pathogenesis
A
- A/B toxin
- leads to ADP ribosylation, excess cAMP
- massive outflow of salt, water
8
Q
staph aureus:
A
