exam I terms Flashcards

1
Q

Th1

A

effector T-cell
makes IFN-y and activates MACs for intracellular microbes
important for NK activation

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2
Q

Th2

A

make IL-4, IL-5
humoral immunity (Ab production)
Anti-parasite responses

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3
Q

Tfh

A

in B cell follicles, needed for B cell differentiation into plasma and memory cells

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3
Q

Treg

A

suppressors, keep infection under control, shut down once infection is cleared. suppress T-cell activation

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3
Q

Th17

A

makes IL-17, stimulates neutrophil responses for extracellular bacteria and fungi

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4
Q

TNF-a

A
  • activates vascular endothelium, increased complement entry
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4
Q

IL-12

A

activates NK cells

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5
Q

IL-6

A

fever

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6
Q

IL-1B

A
  • vascular endothelium permeability
  • local tissue destruction
  • produces IL-6
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7
Q

IL-8

A

basophil, neutrophil recruitment

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8
Q

IFN a/B

A

establish anti-viral state
activate NK cells

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9
Q
A
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10
Q
A
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11
Q
A
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12
Q
A
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