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PLE > Micro: Active Recall > Flashcards

Micro: Active Recall Flashcards

1
Q

Coagulase Positive denotes what organism?

A

Staphyloccocus aureus

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2
Q

Coagulase Negative indicates what further step to differentiate the organism?

A

Novobiocin sensitivity test
Sensitive: S epidermidis
Resistant: S. sapropyticus

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3
Q

Toxin responsible for scarlet fever

A

Erythrogenic toxin

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4
Q

Highly antigenic toxin seen in S. pyogenes causing antibody formation

A

Streptolysin O

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5
Q

Test to document antecedent pharyngitis for RHD

A

ASO (anti-streptolysin O) titer

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6
Q

Weakest defense of the Group A Strep w/c inhibits the complement activation and prevent phagocytosis

A

M protein

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7
Q

Test to document antecedent skin infection in post-strep GN

A

Anti-DNAse B titer

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8
Q

Toxin responsible for the rapid progression of necrotizing fascitis

A

Exotoxin B

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9
Q

Toxin responsible for ascending infection in cellulitis

A

Hyaluronidase (spreading factor)

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10
Q

How do you differentiate from enterococcus and nonenterococcus

A

6.5% NaCl

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11
Q

Pathogenic factor seen in S. pneumoniae responsible for colonization

A

IgA protease

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12
Q

Virulence factor which inhibits a signal transduction in cell division, seen in bacillus anthracis

A

Lethal factor

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13
Q

Calmodulin dependent adenylate cyclase seen in bacillus anthracis

A

Edema factor

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14
Q

Virulence factor seen in anthrax which mediates entry of the other factors into the cell without which, no effects will be manifested

A

Protective antigen

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15
Q

Most common cause of death in anthrax

A

Pulmonary hemorrhage

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16
Q

Bacterial pathogens which produce endospores

A

Bacillus

Clostridium

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17
Q

Emetic form of food poisoning from bacillus cereus implicates which pathogenic factor?

A

Heat stable Enterotoxin

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18
Q

Protease which cleaves proteins involved in glycine release from the spinal cord, seen in Clostridium tetani

A

Tetanospasmin

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19
Q

Pattern of paralysis in Clostridium botulism

A

Descending pattern of flaccid paralysis

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20
Q

Test for toxigenicity of Corynebacterium diphtheriae

A

Modified Elek Test

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21
Q

Forms dark black clononies on potassium tellurite agar

A

Corynebacterium diphtherieae

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22
Q

Shows rapidly spreading growth on egg yolk agar

A

Clostridium perfingens

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23
Q

Drug often implicated in in-hospital clostridium difficile infection

A

Clindamycin

also seen in 2nd and 3rd gen cephalosporins and clindamycin

24
Q

Causes pseudomembranous colitis

A

Clostridium difficile

25
Q

Beta-prophage encoded toxins

A 
[ABCDE]
Shiga-like toxin
Botolinum toxin
Cholera toxin
Diphtheria toxin
Erythrogenic toxin
26
Q

Injection of diphtheria toxin to determine susceptibility to infection

A

Schick test

27
Q

Test designed to indicate whether or not a person is immune to scarlet fever

28
Q

Exhibits tumbling motility

A

Listeria Monocytegenes

29
Q

Pathogenic factor which propels the bacteria through the membranes of one human cell to another, seen in Listeria

A

Actin rockets

30
Q

Antibiotics found in Thayer Martin Agar

A

Vancomycin, Polymyxin/ Colistin, and Nystatin

31
Q

Factors required for growth of H. influenzae on chocolate agar

A 
V factor (NAD)
X factor (hematin)
32
Q

Factor which promotes adherence and invasion into epithelial cells causing opaque colonies, seen in N gonorrheae

A

Opa protein

33
Q

Usual coinfection with Gonorrhea and treatment regimen

A

Chlamydia; Ceftriaxone + Doxycycline

34
Q

Most common cause of epiglottitis

A

Haemophilus influenzae

35
Q

What organism is cultured on Bordet-Gengou agar or Regan Lowe charcoal medium?

A

Bordatella pertussis

36
Q

Factor responsible for “whooping” cough

A

Tracheal cytotoxin

37
Q

Staining used for Legionella

A

Silver stain

38
Q

Where is legionella cultured?

A

Charcoal yeast agar

39
Q

Causative organism of pontiac fever

A

Legionella pneumophila

40
Q

Gram negative rod, lactose fermenter, urease positive

A

Klebsiella pneumoniae

41
Q

What type of agar is used to culture C. jejuni?

A

Skirrow’s agar

42
Q

Produces lactose fermenting colonies on EMB or MacConkey agar

A

Escherichia coli

43
Q

E.coli strain most commonly associated with HUS

44
Q

Organisms implicated in neonatal meningitis

A

Group B Strep
E. coli
Listeria monocytogenes

45
Q

Factor which inhibits the 60S subunit of ribosomes, resulting in decreased protein synthesis in GIT mucosa

A

Shiga-like toxin

46
Q

Factor responsible for pseudomembranes (mucosal cell death)

A

Exotoxin A and B of C difficile

47
Q

Factor which inhibits elongation factor 2 resulting in decreased protein synthesis, seen in pseudomonas

A

Exotocin A of Pseudomonas

48
Q

Test used to detect salmonella antibodies in patient’s serum

A

Widal test

49
Q

Osteomyelitis in burn patients is often caused by:

A

Pseudomonas aeruginosa

50
Q

Osteomyelitis in IV drug abusers is often caused by:

A

Staphylococcus aureus

51
Q

Osteomyelitis in sickle cell anemia

A

Salmonella choleraesuis

52
Q

Exhibits shooting star motility

A

Vibrio cholera

53
Q

Exhibits swarming motility

A

Proteus mirabilis

54
Q

Where is pseudomonas grown

A

Cetrimide agar

55
Q

Medium used to grow Mycobacterium tuberculosis

A

Lowenstein-Jensen medium

56
Q

Most important virulent factor of TB which inhibits WBC migration

A

Cord factor

PLE (8 decks)

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