Gynecology

Question 1

Single most consistent determinant of maleness

Answer 1

Y chromosome specifically the SRY gene

Question 2

Gold standard for identifying sex

Answer 2

Karyotyping

Question 3

At what age of gestation do the ovaries begin to develop in females?

Answer 3

11th or 12th week

Question 4

Structures derived from the mesonephric duct/ Wolffian duct

Answer 4

Vas deferens, epididymis, and seminal vesicles

Question 5

The Wolffian ducts develop in males at what age of gestation?

Answer 5

9th or 10th week

Question 6

The AMH is produced by

Answer 6

Sertoli cells

Question 7

Complete absence of one sex chromosome which presents as short stature, webbed neck, and streak ovaries

Answer 7

Turner Syndrome

Question 8

Meiotic nondisjunction which leads to a 47, XXY genotype presenting as gynecomastia, testicular atrophy, and female-type hair distribution

Answer 8

Klinefelter Syndrome

Question 9

What layer of the endometrium is shed during menstruation?

Answer 9

Stratum functionale

Question 10

Blood supply to the basal 1/3 of the endometrium called the stratum basale

Answer 10

Straight arteries

Question 11

Blood supply to the superficial 2/3 of the endometrium called the stratum functionale

Answer 11

Spiral arteries

Question 12

Narrowest portion of the fallopian tube

Answer 12

Isthmus

Question 13

Site of fertilization and the most common site of ectopic pregnancy

Answer 13

Ampulla

Question 14

Muscle most important in control of urination, parturition, and maintaining fecal continence

Answer 14

Levator ani

Question 15

At which anatomical landmark does the ureter change course and run forward and medially from the uterosacral ligaments to the base of the broad ligament

Answer 15

Level of the ischial spine

Question 16

Narrow window of endometrial receptivity to blastocyst implantation

Answer 16

Days 20-24 of the menstrual cycle

Question 17

Average number of days in a menstrual cycle

Answer 17

25-35 days (new)

28 +/- 7 days (old)

Question 18

Specific location from which GnRH is released from

Answer 18

Arcuate nucleus of the median basal hypothalamus

Question 19

Hormone which acts on the theca celss to stimulate ovarian steroid hormone production

Answer 19

LH

Question 20

Hormone which acts on the granulosa cell to stimulate follicular growth

Answer 20

FSH

Question 21

When is the primary oocyte formed?

Answer 21

5th week AoG

Question 22

Primary oocytes are arrested in which phase?

Answer 22

Prophase

Question 23

Secondary oocytes are arrested in what phase?

Answer 23

Metaphase II

Question 24

What hormone rises in parallel to growth of a dominant follicle?

Answer 24

Estrogen

Question 25

Where are FSH receptors located?

Answer 25

Granulosa cells (on which FSH acts on duh)

Question 26

FSH stimulates conversion of androstenedione by cytochrome P450 into ____.

Answer 26

estradiol

Question 27

Cut-off age for diagnosis of primary amenorrhea

Answer 27

15 years | within 5 years of breast development if occurring by age 10

Question 28

First sign of puberty

Answer 28

Thelarche

Question 29

Last sign of puberty

Answer 29

Menarche

Question 30

Hormone produced by adipocytes which affects LH pulsatility and restore menstrual cycle

Answer 30

Leptin

Question 31

Hormone responsible for breast development

Answer 31

Estradiol

Question 32

Delayed onset puberty, greater wingspan to height ratio, and absent sense of smell due to failed migration of the GnRH neural placodes

Answer 32

Kallmann syndrome

Question 33

Most common cause of hypergonadotrophic hypogonadism

Answer 33

Turner Syndrome

Question 34

Uterovaginal agenesis with a 46 XX karyotype presenting with deafness, normal thelarche and pubarche, streatk uterus, and renal abnormality

Answer 34

Mayer-Rokitansky-Kuster-Hauser Syndrome

Question 35

Absence of menses for an arbitrary period, usually longer than 6 to 12 months

Answer 35

Secondary amenorrhea

Question 36

Pituitary cell destruction due to hemorrhagic loss and hypotension during pregnancy

Answer 36

Sheehan Syndrome

Question 37

Chronic deficiency of the pituitary gland unrelated to pregnancy

Answer 37

Simmonds disease

Question 38

Cut-off age for premature ovarian failure

Answer 38

Menopause before 40yo

Question 39

Scarring of uterine tissue and hence, obliteration of the endometrial cavity from uterine surgery

Answer 39

Asherman syndrome

Question 40

Mutation the G3 protein causing premature menarche; triad of cafe au lait spots, polyostotic fibrous dysplasia, cysts of skull and long bones

Answer 40

McCune Albright Syndrome

Question 41

Pathognomonic sign for labial adhesion

Answer 41

Midline vertical line

Question 42

Inability of a couple to conceive after 1 year of trying

Answer 42

Infertility

Question 43

Anti-acne component of COC

Answer 43

Progestin component

Question 44

Drug associated with liver adenoma

Answer 44

Mestranol