methylprednisolone Flashcards
1
Q
name (trade)
A
solu-medrol
2
Q
class
A
corticosteroid
3
Q
description
A
synthetic steroid with potent anti-inflammatory properties
4
Q
mechanisms of action
A
inhibit substances that cause inflammation (cytokines, interleukin, interleukin, interferon) and inhibit the synthesis of pro-inflammatory enzymes
5
Q
onset
A
IV: varies
other: peak effects 4-8 days (IM)
6
Q
duration
A
1-5 weeks (IM)
7
Q
indications
A
severe anaphylaxis, asthma, COPD
8
Q
contraindications
A
none when used for severe anaphylaxis
9
Q
side effects
A
fluid retention, CHF< HTN, headache, nausea, malaise
10
Q
drug interactions
A
none in the prehospital setting
11
Q
supplied
A
multidose vial of 250 mg
12
Q
dose
A
IV/IM 125-250 mg
