diazepam

Question 1

name (trade)

Answer 1

valium

Question 2

class

Answer 2

benzodiazepine ( lipid soluble)

Question 3

description

Answer 3

sedative-hypnotic, anti convulsing

Question 4

mechanism of action

Answer 4

anxiolytic, sedative, muscle- relaxant, anticonvulsant and amnestic effects.

Question 5

onset

Answer 5

IV: 1-5 minutes

Question 6

duration

Answer 6

15 min - 1 hour

Question 7

indications

Answer 7

seizure activity, premedication prior to countershock or TCP

Question 8

contraindications

Answer 8

hypersensitivity, head injury

Question 9

adverse reactions (side effects)

Answer 9

hypotension, respiratory depression

Question 10

drug indications

Answer 10

dedicated line

Question 11

supplied

Answer 11

pre-filled syringes, multidose vials, tablets

Question 12

dose/administration

Answer 12

IV: seizure: 5mg over 2 min (up to 10 mg for most adults) IV every 10-15 min prn

premedication for cardioversion or TCP: 15 mg IV, 5-10 min prior to procedure

Question 13

special considerations

Answer 13

antidote: flumazenil (romazicon)
reduce dosage by half for ederly