Methoxyflurane

Question 1

What are the indications of Methoxyflurane?

Answer 1

• Pre-hospital pain relief

- Mild/moderate procedural pain

Question 2

What are the contraindications of Methoxyflurane?

Answer 2

• Pre-existing renal disease/impairment
• Muscular dystrophy
• Concurrent tetracycline antibiotic use
• Exceeding 6mL in any 24hr period
• Personal/family history of malignant hyperthermia

Question 3

What are some precautions of Methoxyflurane?

Answer 3

• Pre-eclampsia
• Concurrent Oxytocin (hypotension) use
• Must be held by Pt —> unconsciousness, it will fall from Pt face
• Pt must be supervised at all times during administration

Question 4

What are some side effects of Methoxyflurane?

Answer 4

• Drowsiness
• Decrease blood pressure and bradycardia
• Exceeding 6mL in any 24hr period may lead to renal toxicity

Question 5

What is the dosage of Methoxyflurane?

Answer 5

3mL (repeat of 3mL after 25min). Max 6mL

Question 6

What are some special considerations to Methoxyflurane administration?

Answer 6

• Do not administer in confined space

- Ensure adequate ventilation in ambulance

Question 7

What is the Onset and Duration of Methoxyflurane?

Answer 7

O - 8-10 breaths

D - 25min, 3-5 once no longer inhaling