Fentanyl

Question 1

What are the indications of Fentanyl?

Answer 1

• CPR interfering Pt
• Sedation to maintain intubation
• Analgesia —> hypersensitivity to Morphine, known renal impairment, hypotension, nausea/vomiting, severe headache

Question 2

What are the contraindications of Fentanyl?

Answer 2

• History of hypersensitivity
• Late second stage labour
• Complications with the nose (eg. rhinitis, facial trauma) IN

Question 3

What are some precautions of Fentanyl?

Answer 3

• Elderly/frail Pts
• Respiratory depression (eg. COPD)
• Impaired hepatic function
• Current asthma
• Known addiction to opioids
• Rhinitis, rhinorrhea or facial trauma IN
• Pt >60y/o or Pt <60kg IN

Question 4

What are some side effects of Fentanyl?

Answer 4

• Respiratory depression
• Bradycardia
• Apnoea
• Rigidity of the diaphragm and intercostal muscles

Question 5

What are the dosages of Fentanyl?

Answer 5

• 50mcg at 5min intervals. Consult after 200mcg IV
• 200mcg (repeat 50mcg at 5min intervals) Max 400mcg IN
• F/E/<60kg 100mcg (repeat 50mcg at 5min intervals) Max 200mcg IN
• 100mcg (repeat 50mcg once after 15min) IM
• F/E/<60kg 1mcg/kg IM

Question 6

What is the dilution of Fentanyl?

Answer 6

Dilute Fentanyl 100mcg/2mL to 10mL with 8mL NS

10mg/1mL

Question 7

What is the Onset, Peak and Duration of Fentanyl?

Answer 7

IV
O - immediate 
P - <5min
D - 30-60min
IN
P - 2min