Metals in medicines part 2 Flashcards

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1
Q

what are alkali metals also known as

A

s block metals

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2
Q

what is a property of electrons of s block metals

A

1 electron in their outer shell

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3
Q

how does electronegativity change as you go down the group

A

decreases

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4
Q

how do s block metals appear

A

as salts not in elemental state

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5
Q

how are s block extracted

A

electrolysis starting from naCL or KCL

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6
Q

what is oxidation

A

loss of electron

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7
Q

what is reduction

A

gain of electrons

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8
Q

what is lithium used for

A

manic depression and bipolar disorder

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9
Q

describe the reactivity of lithium

A

lithium as a salt has the smallest ionic radius and is the least reactive of the alkali metals

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10
Q

what are the two isotopes of lithium

A

6LI + 7LI

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11
Q

what are the two isotopes of lithium used for

A

differentiate intra and extra cellular LI+ concentration

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12
Q

what form of lithium is least irritating to the i tract

A

LI2 CO3

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13
Q

how long is lithium monitored for and why

A

12 hours after administration by blood concentration as it has a narrow therapeutic index

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14
Q

is lithium soluble in lipids

A

no

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15
Q

how does lithium enter the cell

A

lithium sodium counter transport
anion exchange
unrelated transport molecules

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16
Q

how does lithium act as a mood stabilizer

A

inhibition of key enzyme in Binding domain

17
Q

what are the adverse effects of lithium

A

tremors
memory problems
extreme doses cause nausea

18
Q

lithium drugs include

A

camcolit
liskonum
priadel

19
Q

what is the main biological role of sodium

A

osmoregulation

functioning of neurons and transmission of nerve impulses

passive transport mechanism

mode of action of several enzymes

20
Q

what is a hypertonic solution

A

that means the solution has a higher concentration of solutes than the surrounding area. This area will gain water through osmosis

21
Q

what is isotonic solution

A

isotonic, that means the solution has the same concentration of solutes as the surrounding area. No movement of water will occur;

22
Q

what is hypotonic solution

A

hypotonic, that means the solution has a lower concentration of solutes than the surrounding area. This area will lose water through osmosis.