mesenchymal tumor markers

Question 1

Tumors of skeletal muscle origin are positive for muscle-specific actin and
desmin and/or other muscle markers such as myo-D1, myoglobin and
myogenin.

a. Fibrohistiocytic tumors
b. Vascular tumors
c. Myogenic tumors
d. Melanomas

Answer 1

c. Myogenic tumors

Question 2

markers such as CD68, or FAM 56,

a. fibrohistiocytic tumors
b. Vascular tumors

Answer 2

a. fibrohistiocytic tumors

Question 3

Endothelial markers (such as angiosarcomas) include
Factor VII-related antigen, CD31 and Ulex Europaeus 1 (UEA).

a. fibrohistiocytic tumors
b. Vascular tumors

Answer 3

b. Vascular tumors

Question 4

Melanocytes are derived from neural crest and will be reactive for S100
protein

a. fibrohistiocytic tumors
b. Vascular tumors
c. melanosome
d.melanomas

Answer 4

d.melanomas

Question 5

a widely used, highly sensitive and highly specific marker for the diagnosis of melanoma.

a. fibrohistiocytic tumors
b. Vascular tumors
c. HMB-45 melanosome
d.melanomas

Answer 5

c. HMB-45 melanosome

Question 6

also encodes a melanoma-specific antigen that is present in normal pigmented cells of skin and retina as well as in certain adrenocortical tumors.

a. melan-a (mart-1)
b.Melanosome (HMB-45)

Answer 6

a. melan-a (mart-1)

Question 7

The best screening marker for lymphoma

a. CD45
b. LCA
c. b cells
d. a and b

Answer 7

d. a and b

Question 8

(CD3, CD4, CDS),

a. Reed-Sternberg cells (
b. B cells:
c. T cells

Answer 8

c. T cells

Question 9

(CD19, CD20, CD23)

a. Reed-Sternberg cells (
b. B cells:
c. T cells

Answer 9

b. B cells:

Question 10

(CD15, CD30

a. Reed-Sternberg cells
b. B cells:
c. T cells

Answer 10

a. Reed-Sternberg cells