Menstrual Disorders Flashcards
the average menstrual cycle lasts how many days?
28 days
between 21 and 35
amenorrhoea is what?
absence of menstruation >6months
menses at intervals of >35days is known as what?
oligomenorrhoea
painful heavy periods can be indicitave of what?
cancer
which is easier to diagnose cervical or uterine cancer?
cevical as can visualise with smear
uterine requires scope/US
which age groups are most likely to be affected by cervical and uterine cancer?
cervical- younger
uterine- older
what is DUB?
dysfunction Uterien Bleeding- bleeding outwith regular cycle
AUB is a diagnosis of?
exclusion
AUB is further subdivided into what two categories?
annovulatory
ovulatory
what kind of bleeding is present in anovulatroy and oviulatory AUB?
anovulatory → irregular cycle
ovulatory → heavy regular bleeding
which type of AUB is more common in women 35-45yrs?
ovulatory
(inadequate progesterone production by corpus luteum)
how is abnormal uterine bleeding investigated?
FBC
cervical smear
TSH
renal/liver function tests
Transvaginal US scan
endometrial sampling
how is AUB managed?
progestons (given day 5-25 then have period)
COCP
progesterone releasing IUCD- mirena
what is the surgical management of AUB?
endometrial resection/ablation
hysterectomy
what hormone therapy is required following endometrial resection/ablation?
combined HRT as oestrogen alone can inc risk of cancer
corpus luteum secretes what?
progesterone
how can the endometrium be imaged/biopsied?
Transvaginal Ultrasound (measures endometrial thickness)
hysteroscopy
endometrial pipelle
dilation and curettage
is biopsy useful during menstrual phase?
no- glands and stroma are falling apart
uterine fibroids are soemtimes named?
leiomyomata
when do endometrial polyps often occur?
around or after menopause
define endometriosis
growht of endometrium outwith the uterus
what cells will be present on histology in endometriosis?
inflammatory cells
what is it called when endometrial glands and stroma break through into the myometrium?
adenomyosis
which drug therapy can cause AUB?
HRT and tamoxifen
(used to control menopausal symtpoms can cause AUB)