Meningitis Flashcards

1
Q

Meningism refers to a symptom complex covering

A

Headache, Photophobia and Vomiting with Muscle Spasm

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2
Q

What type of headache/bleed can cause Meningism

A

Subarachnoid Haeemorhage

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3
Q

What type of neck stiffness is class for meningism

A

Passive Neck Flexion Stiffness

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4
Q

What constitutes the leptomeninges

A

pia and arachnoid

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5
Q

Infections from middle ear may extend into

A

Temporal Lobe

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6
Q

Pathogenesis of Meninigits 5 Steps

A
  1. Attachment into Mucosal Epithelial Cells
  2. Transgression of Mucosal Barrier
  3. Survival in Blood Stream
  4. Entry into CSF
  5. Production of infection in Meninges with or without brain infection (encephalitis)
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7
Q

Which bacteria may cause bacterial meningitis in neonates

A

e coli

group b streptococci

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8
Q

which bacteria may cause bacterial meningitis in children and adults

A

neisseria meningitides or streptococcus pneumonia

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9
Q

10-30% of patients with ventriculo-atrial/peritoneal shunts develop

A

ventriculitis and meningitis

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10
Q

For patients with ventriculo-atrial/peritoneal shunts who develop ventriculitis and meningitis which bacteria is it

A

coagulase neg staphylococci eg staph epidermidis

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11
Q

How is aseptic meningitis confirmed

A

cytology of CSF

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12
Q

Risk factors for Meningitis

A

Alcohol
Recent skull trauma
diabetes

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13
Q

Hypotension of Systolic <90 suggests

A

septic shock

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14
Q

Cranial Nerve palsies are typical of what type of meningitis

A

Tuberculosis or Cryptoccal Meningitis

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15
Q

Papilloedema is unusual in Meningitis. what would you consider instead?

A

intracranial space occupying lesion

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16
Q

Traditional physical signs in Meningitis

A

Kernig Sign

Flex Neck

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17
Q

What is Kernig Sign

A

Hip Flexed

Patient cannot straighten leg due to hamstring spasm in meningism

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18
Q

For patients with focal neurological signs or papilloedema what to do instead of lumbar puncture

A

ct head scan

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19
Q

when is lumbar puncture contraindicated

A

space occupying lesion

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20
Q

What is found in CSF in true meningitis

A

elevated white cells

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21
Q

Which cell type present in CSF for bacterial meningitis

A

Neutrophils

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22
Q

which cell type for viral meningitis or tuberculous meningitis

A

lymphocytes

23
Q

what does glucose do in bacterial and tuberculous meningitis

A

reduced

24
Q

what does protein do in bacterial and tuberculous meningitis

A

great increase

25
Q

Bacterial meningitis 3 organisms

A

Streptocccus Pneumoniae
Neisseria meningitides
Haemophilus Influenza

26
Q

Which antibiotic is good for bacterial meningitis

A

Benzylpenicillin

27
Q

Nesierria Meningitis (meningococcal meningitis) is primarily a disease of

A

Children and young adults

28
Q

What happens in Fulminant Meningococcal Septicaemia

A

Sudden deterioating patient
Septicaemia Shock
Disseminated Intravascular Coagulation

29
Q

What happens in Fulminant Meningococcal Septicaemia to CSF

A

Sterile

Little or No increase in White Cells

30
Q

What is Fulminant Meningococcal related to

A

Waterhouse Frederichsen Syndrome with bilateral adrenal haemorrhages with hypoadrenalism

31
Q

Suspect Meningitis then give

A

Parenteral Penicillin prior to transfer to hospital

32
Q

Acute unwell meningitis parent give

A

High dose Ceftriaxone prior to LP but after taking bloods

33
Q

what should adult patients who had meningitis be given on discharge

A

rifampicin or ciprofloxacin

34
Q

most common bacterial meningitis in adults

A

pneumoccal meinigits

35
Q

predisposing factors to pneumococcal meningitis

A
alcohol
pneumonia
sinusitis
endocarditis
head trauma
splenectomy
36
Q

pneumoccal meningitis on microbiology

A

gram + diploccci

a haemolytic on blood

37
Q

treatment of penumoccal meningitis

A

ceftriazone

38
Q

most common cause of viral meningitis

A

enteroviruses especially echovirus and coxsackie

mumps

39
Q

in the immunocompromised persistent meningitis viral may cause

A

chronic enteroviral meningitis or meningoencephalitis

40
Q

diagnosis for viral meningitis

A

PCR of CSF

Throat Swabs

41
Q

Treatment for Viral Meningitis caused by Herpes

A

Aciclovir

42
Q

Most important cause of meningitis in fungal meningitis

A

cryptococcal meningitis found in bird droppings

43
Q

cryptoccal meningitis is what type of organism

A

polysaccharide

44
Q

fungal meningitis treatment

A

parenteral amphotericin

45
Q

Following fungal meningitis what are patients who have hIV given

A

Long term fluconazole

46
Q

Neonatal meningitis bacterias

A

B Streptocci, E Coli and L Monocytogenes

47
Q

Predisposing factors to neonatal meningitis

A

Low birth weight
prolonged membrane rupture
maternal diabetes

48
Q

Group B Streptocci IN Neonatal Meinigits give

A

Benzyopenicllin and Amoxyciliin or Cefotaxime

49
Q

Listeria monocytogenes in neonatal meningitis - in pregnant women give them

A

ampicillin with gentamicin

50
Q

early onset of neonatal meningitis is classified as

A

within 3 days of birth

51
Q

late onset of neonatal meningitis is classified as

A

more than one week after exams

52
Q

treatment of neonatal meningitis

A

parenteral ampicillin and gentamicin

53
Q

For high risk mothers at risk of passing on neonatal meningitis through group b strep to baby they are given

A

amoxicillin or co amoxiclav whilst pregnant

54
Q

significant risk factors for group b neonatal meningitis

A

pre term delivery <37 weeks
Prolonged interval between membrane rupture and delivery >18 hrs
Previous child had it
Intrapartum Fever