Pyrexia of Unknown Origin Flashcards
1
Q
Fever definition
A
Above 37 degrees
2
Q
Name an endogenous Pyrogen
A
Cytokine
3
Q
Name an exogenous pyrogen
A
Endotoxins
4
Q
Pyrogens act where to cause what in pyrexia of unknown origin
A
hypothalamic thermoregulatory centre to cause reduced heat loss and hence fever
5
Q
Pyrexia of unknown origin classification
A
- temp >38.3
- recorded on multiple occasions
- present for at least three weeks
6
Q
what is nosocomial puo
A
develops in hospital, undiagnosed after 3 days
7
Q
what is neutropenic puo?
A
undiagnosed fever in patient with neutrophils <500/mm3
8
Q
HIV associated PUO
A
present and undiagnosed for more than 3 days in hospital or 4 weeks outpatient
9
Q
Which bacteria causes HIV related PUO (2)
A
Mycobacterium TB
Mycobacterium Avium
