Memory part 2 Flashcards
1
Q
What defines alzheimer’s disease?
A
Extracellular amyloid plaques
Intracellular neurofibrillary tangles
Inflammation
2
Q
What causes amyloid plaques to accumulate?
A
Increase production of amyloid peptides
Impaired elimination of peptides
3
Q
What does accumulation of plaques induce?
A
Apoptosis
4
Q
What does tangles and plaques do?
A
Contributes to brain degeneration and targets hippocampal formation
